Ethyl {1-[(4-methylphenyl)sulfonyl]-3-oxopiperazin-2-yl}acetate

Base Information

Chemical Name:Ethyl {1-[(4-methylphenyl)sulfonyl]-3-oxopiperazin-2-yl}acetate
CAS No.:318288-64-1
Molecular Formula:C₁₅H₂₀N₂O₅S
Molecular Weight:340.4
Hs Code.:
DSSTox Substance ID:DTXSID201185831
ChEMBL ID:CHEMBL1579378

Synonyms:318288-64-1;ethyl {1-[(4-methylphenyl)sulfonyl]-3-oxopiperazin-2-yl}acetate;ethyl 2-[1-(4-methylbenzenesulfonyl)-3-oxopiperazin-2-yl]acetate;ethyl 2-(3-oxo-1-tosylpiperazin-2-yl)acetate;ethyl 2-{1-[(4-methylphenyl)sulfonyl]-3-oxo-2-piperazinyl}acetate;Oprea1_014615;MLS000716873;CHEMBL1579378;DTXSID201185831;HMS2661P03;ethyl 2-[1-(4-methylphenyl)sulfonyl-3-oxopiperazin-2-yl]acetate;MFCD00173284;STK203634;AKOS000613766;AKOS016160303;5H-427S;SMR000278390;CS-0327882;Ethyl 1-[(4-methylphenyl)sulfonyl]-3-oxo-2-piperazineacetate;ethyl2-[1-(4-methylbenzenesulfonyl)-3-oxopiperazin-2-yl]acetate

Suppliers and Price of Ethyl {1-[(4-methylphenyl)sulfonyl]-3-oxopiperazin-2-yl}acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL-2-(1-((4-METHYLPHENYL)SULFONYL)-3-OXO-2-PIPERAZINYL)ACETATE 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
ETHYL-2-(1-((4-METHYLPHENYL)SULFONYL)-3-OXO-2-PIPERAZINYL)ACETATE 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
ETHYL-2-(1-((4-METHYLPHENYL)SULFONYL)-3-OXO-2-PIPERAZINYL)ACETATE 95.00%
1MG
$ 647.61

Total 2 raw suppliers

Chemical Property of Ethyl {1-[(4-methylphenyl)sulfonyl]-3-oxopiperazin-2-yl}acetate

Chemical Property:

Density:1.271±0.06 g/cm3(Predicted)
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:340.10929292
Heavy Atom Count:23
Complexity:535

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-2-(1-((4-METHYLPHENYL)SULFONYL)-3-OXO-2-PIPERAZINYL)ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC1C(=O)NCCN1S(=O)(=O)C2=CC=C(C=C2)C

Technology Process of Ethyl {1-[(4-methylphenyl)sulfonyl]-3-oxopiperazin-2-yl}acetate

There total 1 articles about Ethyl {1-[(4-methylphenyl)sulfonyl]-3-oxopiperazin-2-yl}acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 33422-35-4,686300-89-0
ethyl 2-(3-oxopiperazin-2-yl)acetate

: 318288-64-1
C₁₅H₂₀N₂O₅S

Guidance literature:: With pyridine;
DOI:10.1016/j.bmcl.2011.03.115

Reference yield:

: 318288-64-1
C₁₅H₂₀N₂O₅S

: 828914-34-7
[3-oxo-1-(toluene-4-sulfonyl)-piperazin-2R-yl]-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: water; lithium hydroxide / 1,4-dioxane; methanol

2: methanol

3: sulfuric acid / water

With sulfuric acid; water; lithium hydroxide; In 1,4-dioxane; methanol; water;
DOI:10.1016/j.bmcl.2011.03.115

Reference yield:

: 318288-64-1
C₁₅H₂₀N₂O₅S

: 2-[3-oxo-1-(toluene-4-sulfonyl)piperazin-2(R,S)-yl]-N-(6-piperidin-1-ylmethyl-1,2,3,4-tetrahydronaphthalen-1(R)-yl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: water; lithium hydroxide / 1,4-dioxane; methanol

2: acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / isopropyl alcohol

With water; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In 1,4-dioxane; methanol; isopropyl alcohol;
DOI:10.1016/j.bmcl.2011.03.115