C₂₉H₃₆N₂O₅

Base Information

• Chemical Name: C₂₉H₃₆N₂O₅
• CAS No.: 1387636-74-9
• Molecular Formula: C₂₉H₃₆N₂O₅
• Molecular Weight: 492.615
• Mol file: 1387636-74-9.mol

Synonyms:

Chemical Property of C₂₉H₃₆N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₆N₂O₅

There total 4 articles about C₂₉H₃₆N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Tetrahydro-4H-pyran-4-one (29943-42-8,143562-54-3) + C20H22N2O4 (1387636-59-0) + Cyclopropanecarboxaldehyde (1489-69-6) → C29H36N2O5 (1387636-74-9)

Guidance literature:

With 2-methylpyridine borane complex; acetic acid; In methanol; at 20 ℃;

DOI:10.1016/j.bmcl.2012.05.066

Reference yield:

2-chloro-3-methyl-5-nitroquinoline (1387636-49-8) → C29H36N2O5 (1387636-74-9)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium phosphate; palladium diacetate; tert-butyl XPhos / toluene / Reflux

2: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

3: 2-methylpyridine borane complex; acetic acid / methanol / 20 °C

With potassium phosphate; 2-methylpyridine borane complex; palladium on activated charcoal; hydrogen; palladium diacetate; acetic acid; tert-butyl XPhos; In methanol; ethyl acetate; toluene;

DOI:10.1016/j.bmcl.2012.05.066

Reference yield:

C20H20N2O6 (1387636-54-5) → C29H36N2O5 (1387636-74-9)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

2: 2-methylpyridine borane complex; acetic acid / methanol / 20 °C

With 2-methylpyridine borane complex; palladium on activated charcoal; hydrogen; acetic acid; In methanol; ethyl acetate;

DOI:10.1016/j.bmcl.2012.05.066

upstream raw materials:

Tetrahydro-4H-pyran-4-one

C₂₀H₂₂N₂O₄

Cyclopropanecarboxaldehyde

2-chloro-3-methyl-5-nitroquinoline

Refernces