C₁₂H₁₀N₂O₃

Base Information

Chemical Name:C₁₂H₁₀N₂O₃
CAS No.:1263079-08-8
Molecular Formula:C₁₂H₁₀N₂O₃
Molecular Weight:230.223
Hs Code.:

C<sub>12</sub>H<sub>10</sub>N<sub>2</sub>O<sub>3</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₂H₁₀N₂O₃

Chemical Property:

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Technology Process of C₁₂H₁₀N₂O₃

There total 4 articles about C₁₂H₁₀N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 667886-02-4
C₁₄H₁₄N₂O₃

: 1263079-08-8
C₁₂H₁₀N₂O₃

Guidance literature:: C₁₄H₁₄N₂O₃; With boron tribromide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

With water; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ic1019422

Reference yield:

: 1263079-04-4
BrH*C₁₂H₁₀N₂O₃

: 1263079-08-8
C₁₂H₁₀N₂O₃

Guidance literature:: With tetramethyl ammoniumhydroxide; In water; acetonitrile; at 20 ℃;
DOI:10.1021/ic1019422

Reference yield:

: 504-24-5
4-aminopyridine

: 1263079-08-8
C₁₂H₁₀N₂O₃

Guidance literature:: Multi-step reaction with 2 steps

1.1: dmap; triethylamine; 4-Nitrobenzenesulfonyl chloride / N,N-dimethyl-formamide / 0.33 h

1.2: 0 - 20 °C

2.1: boron tribromide / dichloromethane / 0 - 20 °C / Inert atmosphere

2.2: 2 h / 0 °C / Inert atmosphere

With dmap; boron tribromide; triethylamine; 4-Nitrobenzenesulfonyl chloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ic1019422