acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7

Base Information

• Chemical Name: acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7
• CAS No.: 110346-42-4
• Molecular Formula: C₂₇H₄₅BrO₅
• Molecular Weight: 529.555
• Mol file: 110346-42-4.mol

Synonyms:

Chemical Property of acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7

There total 2 articles about acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

acide bromo-2β oxo-3 seco-6,7 (5β) cholestane dioique-6,7 (110372-09-3) → acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7 (110346-42-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; diethyl ether; for 2h;

Reference yield:

acide oxo-3 seco-6,7 (5β) cholestane dioique-6,7 (28097-22-5,110346-39-9) → acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7 (110346-42-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 36 percent / HBr, Br₂ / acetic acid / 0.25 h

2: 35 percent / NaBH₄ / methanol; diethyl ether / 2 h

With sodium tetrahydroborate; hydrogen bromide; bromine; In methanol; diethyl ether; acetic acid;

Reference yield: 75.0%

acetic anhydride (108-24-7) + acide bromo-2α hydroxy-3α seco-6,7 (5β) cholestane dioique-6,7 (110346-42-4) → acide acetoxy-3α bromo-2α seco-6,7 (5β) cholestane dioique-6,7 γ-lactone (110346-46-8)

Guidance literature:

With sodium acetate; for 1.5h; Heating;

upstream raw materials:

acide bromo-2β oxo-3 seco-6,7 (5β) cholestane dioique-6,7

acide oxo-3 seco-6,7 (5β) cholestane dioique-6,7

Downstream raw materials:

acide acetoxy-3α bromo-2α seco-6,7 (5β) cholestane dioique-6,7 γ-lactone