Technology Process of C21H21NO6
There total 9 articles about C21H21NO6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C21H21NO5;
With
C27H33F6N7O2*ClH; potassium carbonate;
In
toluene;
at 0 - 20 ℃;
for 0.166667h;
With
Cumene hydroperoxide;
In
toluene;
at 0 ℃;
for 24h;
Overall yield = 90 %; enantioselective reaction;
DOI:10.1002/chem.201303633
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetic acid
2.1: potassium carbonate; C27H33F6N7O2*ClH / toluene / 0.17 h / 0 - 20 °C
2.2: 24 h / 0 °C
With
C27H33F6N7O2*ClH; potassium carbonate; acetic acid;
In
toluene;
DOI:10.1002/chem.201303633
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium hydride / N,N-dimethyl-formamide
2.1: acetic acid; hydrogen
3.1: acetic acid; sodium nitrite; pyridine / acetic anhydride
3.2: 60 h
4.1: lithium hydroxide / methanol; water
5.1: acetic acid
6.1: potassium carbonate; C27H33F6N7O2*ClH / toluene / 0.17 h / 0 - 20 °C
6.2: 24 h / 0 °C
With
pyridine; C27H33F6N7O2*ClH; hydrogen; sodium hydride; potassium carbonate; acetic acid; lithium hydroxide; sodium nitrite;
In
methanol; water; acetic anhydride; N,N-dimethyl-formamide; toluene;
DOI:10.1002/chem.201303633