Ethyl (2E)-2,3-dimethyl-4-phenyl-2-butenoate

Base Information

Chemical Name:Ethyl (2E)-2,3-dimethyl-4-phenyl-2-butenoate
CAS No.:139244-08-9
Molecular Formula:C14H18O2
Molecular Weight:218.296
Hs Code.:
DSSTox Substance ID:DTXSID501259752
Nikkaji Number:J469.458I

Synonyms:SCHEMBL15101103;DTXSID501259752;139244-08-9;Ethyl (2E)-2,3-dimethyl-4-phenyl-2-butenoate

Suppliers and Price of Ethyl (2E)-2,3-dimethyl-4-phenyl-2-butenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Ethyl (2E)-2,3-dimethyl-4-phenyl-2-butenoate

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:218.130679813
Heavy Atom Count:16
Complexity:260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(=C(C)CC1=CC=CC=C1)C
Isomeric SMILES:CCOC(=O)/C(=C(\C)/CC1=CC=CC=C1)/C

Technology Process of Ethyl (2E)-2,3-dimethyl-4-phenyl-2-butenoate

There total 7 articles about Ethyl (2E)-2,3-dimethyl-4-phenyl-2-butenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3699-66-9
ethyl 2-diethoxyphosphorylpropionate

: 103-79-7,136675-26-8
1-phenyl-acetone

: 139244-08-9
(Z)-Ethyl 4-Phenyl-2,3-dimethyl-2-butenoate

: 139244-09-0
(E)-Ethyl 4-Phenyl-2,3-dimethyl-2-butenoate

Guidance literature:: ethyl 2-diethoxyphosphorylpropionate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

1-phenyl-acetone; In tetrahydrofuran; for 22h; Overall yield = 97.6 mg;

Reference yield:

: 103-79-7,136675-26-8
1-phenyl-acetone

: 139244-08-9
(Z)-Ethyl 4-Phenyl-2,3-dimethyl-2-butenoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hexamethyldisilazide / tetrahydrofuran; toluene / 0.17 h / -78 °C

1.2: tetrahydrofuran; toluene / -78 - 20 °C

2.1: Sml₂ / tetrahydrofuran / 2 h / Heating

With samarium diiodide; potassium hexamethylsilazane; In tetrahydrofuran; toluene;
DOI:10.1021/ol016894p

Reference yield:

: 535-13-7
2-chloro-propanoic acid, ethyl ester

: 139244-08-9
(Z)-Ethyl 4-Phenyl-2,3-dimethyl-2-butenoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hexamethyldisilazide / tetrahydrofuran; toluene / 0.17 h / -78 °C

1.2: tetrahydrofuran; toluene / -78 - 20 °C

2.1: Sml₂ / tetrahydrofuran / 2 h / Heating

With samarium diiodide; potassium hexamethylsilazane; In tetrahydrofuran; toluene;
DOI:10.1021/ol016894p