C₂₂H₂₄O₅

Base Information

• Chemical Name: C₂₂H₂₄O₅
• CAS No.: 109421-04-7
• Molecular Formula: C₂₂H₂₄O₅
• Molecular Weight: 368.43
• Mol file: 109421-04-7.mol

Synonyms:

Chemical Property of C₂₂H₂₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄O₅

There total 11 articles about C₂₂H₂₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-(S)-1-Bromo-oct-1-en-3-ol (120293-90-5) → C22H24O5 (109421-04-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 84 percent / Ni(dppp)Cl₂ / diethyl ether / 3 h / Ambient temperature; addition at 0 deg C

2: 1.) mCPBA, NaHCO₃, 2.) ⁿBu₄NF / 1.) CH₂Cl₂, 0 deg C, 1 h, 2.) THF, 0 deg C, 0.5 h

3: pyridine / Ambient temperature

4: 1.) O₃, 2.) Me₂S / 1.) MeOH, -78 deg C

With dimethylsulfide; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; ozone; 3-chloro-benzenecarboperoxoic acid; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In pyridine; diethyl ether;

DOI:10.1016/S0040-4039(00)80846-1

Reference yield:

(S)-1,2-Dibromo-1-trimethylsilanyl-octan-3-ol (126531-34-8,126640-08-2) → C22H24O5 (109421-04-7)

Guidance literature:

Multi-step reaction with 5 steps

1: ⁿBu₄NF / tetrahydrofuran / 0 °C

2: 84 percent / Ni(dppp)Cl₂ / diethyl ether / 3 h / Ambient temperature; addition at 0 deg C

3: 1.) mCPBA, NaHCO₃, 2.) ⁿBu₄NF / 1.) CH₂Cl₂, 0 deg C, 1 h, 2.) THF, 0 deg C, 0.5 h

4: pyridine / Ambient temperature

5: 1.) O₃, 2.) Me₂S / 1.) MeOH, -78 deg C

With dimethylsulfide; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; ozone; 3-chloro-benzenecarboperoxoic acid; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; pyridine; diethyl ether;

DOI:10.1016/S0040-4039(00)80846-1

Reference yield:

(E)-1-(trimethylsilyl)oct-1-en-3-ol (109423-06-5) → C22H24O5 (109421-04-7)

Guidance literature:

Multi-step reaction with 7 steps

1: tBuOOH, Ti(OiPr)4, D-(-)-diisopropyl tartrate / CH₂Cl₂

2: Br₂ / CH₂Cl₂ / -20 °C

3: ⁿBu₄NF / tetrahydrofuran / 0 °C

4: 84 percent / Ni(dppp)Cl₂ / diethyl ether / 3 h / Ambient temperature; addition at 0 deg C

5: 1.) mCPBA, NaHCO₃, 2.) ⁿBu₄NF / 1.) CH₂Cl₂, 0 deg C, 1 h, 2.) THF, 0 deg C, 0.5 h

6: pyridine / Ambient temperature

7: 1.) O₃, 2.) Me₂S / 1.) MeOH, -78 deg C

With titanium(IV) isopropylate; tert.-butylhydroperoxide; dimethylsulfide; tetrabutyl ammonium fluoride; bromine; sodium hydrogencarbonate; D-(-)-diisopropyl tartrate; ozone; 3-chloro-benzenecarboperoxoic acid; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; pyridine; diethyl ether; dichloromethane;

DOI:10.1016/S0040-4039(00)80846-1

upstream raw materials:

benzoyl chloride

(1R,2S)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-heptane-1,2-diol

(1R,2S)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1-(2-ethoxy-ethoxy)-heptan-2-ol

(Z)-(S)-1-Bromo-oct-1-en-3-ol