2-(4-Hydroxy-2,6-dimethylphenyl)acetic acid

Base Information

Chemical Name:2-(4-Hydroxy-2,6-dimethylphenyl)acetic acid
CAS No.:21354-74-5
Molecular Formula:C₁₀H₁₂O₃
Molecular Weight:180.203
Hs Code.:
DSSTox Substance ID:DTXSID001276298

Synonyms:2-(4-Hydroxy-2,6-dimethylphenyl)acetic acid;21354-74-5;SCHEMBL9780872;AHBSZAKDLWLFCF-UHFFFAOYSA-N;DTXSID001276298;4-Hydroxy-2,6-dimethylbenzeneacetic acid;EN300-3007957;Z1262518831

Suppliers and Price of 2-(4-Hydroxy-2,6-dimethylphenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(4-Hydroxy-2,6-dimethylphenyl)acetic acid

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:180.078644241
Heavy Atom Count:13
Complexity:179

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC(=C1CC(=O)O)C)O

Technology Process of 2-(4-Hydroxy-2,6-dimethylphenyl)acetic acid

There total 5 articles about 2-(4-Hydroxy-2,6-dimethylphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 33901-24-5
4-Cyanomethyl-3,5-dimethylphenol

: 21354-74-5
4-Hydroxy-2,6-dimethylphenylacetic acid

Guidance literature:: With potassium hydroxide; ethylene glycol; for 3h; Heating;

Reference yield:

: 54373-50-1
O-ethoxycarbonyl-3,5-dimethyl-4-chloromethylphenol

: 21354-74-5
4-Hydroxy-2,6-dimethylphenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / dimethylformamide / 1) RT; 2) reflux, 2 h

2: 68 percent / KOH, ethylene glycol / 3 h / Heating

With potassium hydroxide; ethylene glycol; In N,N-dimethyl-formamide;

Reference yield:

: 26177-58-2
3,5-Dimethylphenyl ethyl carbonate

: 21354-74-5
4-Hydroxy-2,6-dimethylphenylacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 52 percent / HCl-gas, conc. HCl acid / 1) 0.5 deg C, 1 h; 2) 25 deg C, 3 h

2: 75 percent / dimethylformamide / 1) RT; 2) reflux, 2 h

3: 68 percent / KOH, ethylene glycol / 3 h / Heating

With hydrogenchloride; potassium hydroxide; ethylene glycol; In N,N-dimethyl-formamide;