3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid

Base Information

Chemical Name:3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid
CAS No.:43071-46-1
Molecular Formula:C₁₈H₁₅NO₂
Molecular Weight:277.323
Hs Code.:
DSSTox Substance ID:DTXSID801207786

Synonyms:43071-46-1;3-methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid;3-METHYL-2-(P-TOLYL)QUINOLINE-4-CARBOXYLIC ACID;3-Methyl-2-p-tolyl-quinoline-4-carboxylic acid;3-methyl-2-p-tolylquinoline-4-carboxylic acid;Oprea1_285716;Oprea1_354481;DTXSID801207786;BBL014118;MFCD00783442;STK389247;AKOS000576691;SB69037;NCGC00280667-01;10440-74-1;AS-38774;CS-0046151;AB01281019-01;SR-01000909094;SR-01000909094-1;Z57127957;3-methyl-2-(4-methylphenyl)-4-quinolinecarboxylic acid;3-METHYL-2-(P-TOLYL)QUINOLINE-4-CARBOXYLICACID;F1773-0088

Suppliers and Price of 3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid
1g
$ 331.00

Matrix Scientific
3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid
500mg
$ 215.00

Crysdot
3-Methyl-2-(p-tolyl)quinoline-4-carboxylicacid 97%
1g
$ 657.00

Chemenu
3-Methyl-2-(p-tolyl)quinoline-4-carboxylicacid 97%
1g
$ 621.00

Total 3 raw suppliers

Chemical Property of 3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:277.110278721
Heavy Atom Count:21
Complexity:375

Purity/Quality:

98%min ^*data from raw suppliers

3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=C2C)C(=O)O
Uses 3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic Acid can be used to treat cancer.

Technology Process of 3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid

There total 5 articles about 3-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 43170-64-5
3-(carboxymethyl)-2-(4-methylphenyl)quinoline-4-carboxylic acid

: 43071-46-1
3-methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid

Guidance literature:: In nitrobenzene; for 1h; Reflux;
DOI:10.1002/jhet.2529

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 43071-46-1
3-methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol / 12 h / Reflux

2: nitrobenzene / 1 h / Reflux

With potassium hydroxide; In ethanol; nitrobenzene; 1: |Pfitzinger Quinoline Synthesis;
DOI:10.1002/jhet.2529

Reference yield:

: 4619-20-9
3-(4-methylbenzoyl)propionic acid

: 43071-46-1
3-methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol / 12 h / Reflux

2: nitrobenzene / 1 h / Reflux

With potassium hydroxide; In ethanol; nitrobenzene; 1: |Pfitzinger Quinoline Synthesis;
DOI:10.1002/jhet.2529