C₃₁H₄₃F₃N₄O₅S₂

Base Information

• Chemical Name: C₃₁H₄₃F₃N₄O₅S₂
• CAS No.: 1359738-95-6
• Molecular Formula: C₃₁H₄₃F₃N₄O₅S₂
• Molecular Weight: 672.833
• Mol file: 1359738-95-6.mol

Synonyms:

Chemical Property of C₃₁H₄₃F₃N₄O₅S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₄₃F₃N₄O₅S₂

There total 3 articles about C₃₁H₄₃F₃N₄O₅S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-ethyl-2-(4-methanesulfonyl-phenyl)-N-piperidin-4-yl-acetamide (374725-04-9) → C31H43F3N4O5S2 (1359738-95-6)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 80 - 90 °C

2: methanesulfonyl chloride; triethylamine / dichloromethane / 0 °C

3: triethylamine / dichloromethane / 20 °C

With potassium carbonate; methanesulfonyl chloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.12.117

Reference yield:

C25H34N2O4S (527693-73-8) → C31H43F3N4O5S2 (1359738-95-6)

Guidance literature:

Multi-step reaction with 2 steps

1: methanesulfonyl chloride; triethylamine / dichloromethane / 0 °C

2: triethylamine / dichloromethane / 20 °C

With methanesulfonyl chloride; triethylamine; In dichloromethane;

DOI:10.1016/j.bmcl.2011.12.117

Reference yield:

(S)-3-hydroxy-3-phenylpropyl 4-methylbenzenesulfonate (156453-52-0) → C31H43F3N4O5S2 (1359738-95-6)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 80 - 90 °C

2: methanesulfonyl chloride; triethylamine / dichloromethane / 0 °C

3: triethylamine / dichloromethane / 20 °C

With potassium carbonate; methanesulfonyl chloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.12.117

upstream raw materials:

N-ethyl-2-(4-methanesulfonyl-phenyl)-N-piperidin-4-yl-acetamide

C₂₅H₃₄N₂O₄S

(S)-3-hydroxy-3-phenylpropyl 4-methylbenzenesulfonate