tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate

Base Information

Chemical Name:tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate
CAS No.:1402069-90-2
Molecular Formula:C₁₉H₂₃NO₆
Molecular Weight:361.395
Hs Code.:

Synonyms:

Suppliers and Price of tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate

There total 7 articles about tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1402069-79-7
(2R,3R,E)-Methyl 2-(tert-butoxycarbonylamino)-3-(7-methoxybenzo[d]-ACHTUNGTRENUNG[1,3]dioxol-5-yl)hex-4-enoate

: 1402069-90-2
tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate

Guidance literature:: Multi-step reaction with 4 steps

1: perchloric acid; palladium diacetate; p-benzoquinone / water; acetonitrile / 6 h / 20 °C

2: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 °C

3: camphor-10-sulfonic acid / toluene / 4 h / 80 °C

4: diisobutylaluminium hydride

With perchloric acid; camphor-10-sulfonic acid; potassium tert-butylate; palladium diacetate; diisobutylaluminium hydride; p-benzoquinone; In tetrahydrofuran; water; toluene; acetonitrile; 1: Wacker oxidation;
DOI:10.1002/chem.201201649

Reference yield:

: 1402069-91-3
C₁₉H₂₅NO₇

: 1402069-90-2
tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate

Guidance literature:: Multi-step reaction with 5 steps

1: methanol; diethyl ether / 1 h

2: perchloric acid; palladium diacetate; p-benzoquinone / water; acetonitrile / 6 h / 20 °C

3: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 °C

4: camphor-10-sulfonic acid / toluene / 4 h / 80 °C

5: diisobutylaluminium hydride

With perchloric acid; camphor-10-sulfonic acid; potassium tert-butylate; palladium diacetate; diisobutylaluminium hydride; p-benzoquinone; In tetrahydrofuran; methanol; diethyl ether; water; toluene; acetonitrile; 2: Wacker oxidation;
DOI:10.1002/chem.201201649

Reference yield:

: 654061-13-9
(R)-4-(7-methoxybenzo[1,3]dioxol-5-yl)but-3-en-2-ol

: 1402069-90-2
tert-butyl (1R,6R)-6-(7-methoxybenzo[d][1,3]dioxol-5-yl)-2-oxocyclohex-3-enylcarbamate

Guidance literature:: Multi-step reaction with 7 steps

1.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 2 h / 0 - 20 °C

2.1: tert-butyldimethylsilyl chloride; lithium hexamethyldisilazane / tetrahydrofuran / 20 h / -78 - 20 °C

2.2: 0 - 20 °C

3.1: methanol; diethyl ether / 1 h

4.1: perchloric acid; palladium diacetate; p-benzoquinone / water; acetonitrile / 6 h / 20 °C

5.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 °C

6.1: camphor-10-sulfonic acid / toluene / 4 h / 80 °C

7.1: diisobutylaluminium hydride

With dmap; perchloric acid; camphor-10-sulfonic acid; potassium tert-butylate; palladium diacetate; diisobutylaluminium hydride; tert-butyldimethylsilyl chloride; dicyclohexyl-carbodiimide; p-benzoquinone; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; toluene; acetonitrile; 4.1: Wacker oxidation;
DOI:10.1002/chem.201201649