bicyclo[2.2.1]heptane-1,4-diamine dihydrochloride

Base Information

• Chemical Name: bicyclo[2.2.1]heptane-1,4-diamine dihydrochloride
• CAS No.: 1818847-46-9
• Molecular Formula: C₇H₁₄N₂*2ClH
• Molecular Weight: 199.123
• Mol file: 1818847-46-9.mol

Synonyms:

Chemical Property of bicyclo[2.2.1]heptane-1,4-diamine dihydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Bicyclo[2.2.1]heptane-1,4-diaminedihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bicyclo[2.2.1]heptane-1,4-diamine dihydrochloride

There total 2 articles about bicyclo[2.2.1]heptane-1,4-diamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bicyclo<2.2.1>heptane-1,4-dicarboxylic acid (15544-51-1) → bicyclo[2.2.1]heptane-1,4-diamine dihydrochloride (1818847-46-9)

Guidance literature:

bicyclo<2.2.1>heptane-1,4-dicarboxylic acid; With trimethylsilylazide; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine; In ethyl acetate; toluene; at 20 - 90 ℃; for 4h;

With hydrogenchloride; In water; at 50 ℃;

Reference yield:

dimethyl bicyclo<2.2.1>heptane-1,4-dicarboxylate (15448-76-7) → bicyclo[2.2.1]heptane-1,4-diamine dihydrochloride (1818847-46-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: water; lithium hydroxide monohydrate / methanol / 72 h / 20 °C

2.1: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; trimethylsilylazide; triethylamine / toluene; ethyl acetate / 4 h / 20 - 90 °C

2.2: 50 °C

With lithium hydroxide monohydrate; trimethylsilylazide; water; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine; In methanol; ethyl acetate; toluene;

upstream raw materials:

bicyclo<2.2.1>heptane-1,4-dicarboxylic acid

dimethyl bicyclo<2.2.1>heptane-1,4-dicarboxylate