(+/-)-pyrene trans-4,5-dihydrodiol

Base Information

• Chemical Name: (+/-)-pyrene trans-4,5-dihydrodiol
• CAS No.: 101226-68-0
• Molecular Formula: C₁₆H₁₂O₂
• Molecular Weight: 236.27
• Mol file: 101226-68-0.mol

Synonyms:

Chemical Property of (+/-)-pyrene trans-4,5-dihydrodiol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-pyrene trans-4,5-dihydrodiol

There total 4 articles about (+/-)-pyrene trans-4,5-dihydrodiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4,5-dihydroxypyrene (83500-79-2) → (+/-)-pyrene trans-4,5-dihydrodiol (101226-68-0,28622-70-0,56183-12-1)

Guidance literature:

With sodium tetrahydroborate; oxygen; In ethanol; for 24h; Ambient temperature;

DOI:10.1055/s-1982-29834

Reference yield: 85.0%

pyrene-4,5-dione (6217-22-7) → (+/-)-pyrene trans-4,5-dihydrodiol (101226-68-0,28622-70-0,56183-12-1)

Guidance literature:

With sodium tetrahydroborate; oxygen; In ethanol; for 24h; Ambient temperature;

DOI:10.1055/s-1982-29834

Reference yield:

cis-4,5-Dihydro-4,5-dihydroxypyrene (51689-88-4,1251472-76-0,28622-70-0,56183-12-1) → (+/-)-pyrene trans-4,5-dihydrodiol (101226-68-0,28622-70-0,56183-12-1)

Guidance literature:

Multi-step reaction with 2 steps

1: MnO₂ / CH₂Cl₂

2: KBH₄ / propan-2-ol / Ambient temperature

With manganese(IV) oxide; potassium borohydride; In dichloromethane; isopropyl alcohol;

DOI:10.1021/jo00360a024

upstream raw materials:

pyrene-4,5-dione

4,5-dihydroxypyrene

cis-4,5-Dihydro-4,5-dihydroxypyrene

Downstream raw materials:

(4R,5R)-trans-4,5-dihydroxy-4,5-dihydropyrene

(-)-pyrene (4S,5S)-dihydrodiol