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(Z)-5-(4-bromophenyl)pent-4-enoic acid

Base Information
  • Chemical Name:(Z)-5-(4-bromophenyl)pent-4-enoic acid
  • CAS No.:1379786-07-8
  • Molecular Formula:C11H11BrO2
  • Molecular Weight:255.111
  • Hs Code.:
(Z)-5-(4-bromophenyl)pent-4-enoic acid

Synonyms:

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Chemical Property of (Z)-5-(4-bromophenyl)pent-4-enoic acid
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Technology Process of (Z)-5-(4-bromophenyl)pent-4-enoic acid

There total 2 articles about (Z)-5-(4-bromophenyl)pent-4-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With water; lithium hydroxide; In tetrahydrofuran; at 25 ℃; Inert atmosphere;
DOI:10.1039/c2cc31148h
Guidance literature:
Multi-step reaction with 2 steps
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C
1.2: Wittig Olefination / -78 - 20 °C
2.1: water; lithium hydroxide / methanol / 2 h / 100 °C
With water; sodium hexamethyldisilazane; lithium hydroxide; In tetrahydrofuran; methanol; 1.1: |Wittig Olefination;
DOI:10.1039/c9cc07466j
Guidance literature:
With N-Bromosuccinimide; C35H45N3O4S; In hexane; chloroform; at -60 ℃; for 70h; optical yield given as %ee; enantioselective reaction; Darkness; Inert atmosphere;
DOI:10.1039/c2cc31148h
upstream raw materials:

4-bromo-benzaldehyde

Downstream raw materials:

5-(bromo(p-bromophenyl)methyl)dihydrofuran-2(3H)-one

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