C₁₂H₁₂O₂

Base Information

• Chemical Name: C₁₂H₁₂O₂
• CAS No.: 1332831-69-2
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.226
• Mol file: 1332831-69-2.mol

Synonyms:

Chemical Property of C₁₂H₁₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₂O₂

There total 4 articles about C₁₂H₁₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H12O2 → C12H12O2 (1332831-69-2) + 6-(o-tolyl)-5,6-dihydro-2H-pyran-2-one (1332831-68-1)

Guidance literature:

With 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; potassium tert-butylate; In dichloromethane; at 20 ℃; for 24h; Reflux; Inert atmosphere;

DOI:10.1039/c1ob05854a

Reference yield:

3-(2-tolyl)-oxirane-2-carbaldehyde → C12H12O2 (1332831-69-2) + 6-(o-tolyl)-5,6-dihydro-2H-pyran-2-one (1332831-68-1)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 0.33 h / Inert atmosphere; Reflux

2: 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; potassium tert-butylate / dichloromethane / 24 h / 20 °C / Reflux; Inert atmosphere

With 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; potassium tert-butylate; In dichloromethane; acetonitrile;

DOI:10.1039/c1ob05854a

Reference yield:

2-methylphenyl aldehyde (529-20-4) → C12H12O2 (1332831-69-2) + 6-(o-tolyl)-5,6-dihydro-2H-pyran-2-one (1332831-68-1)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium / 24 h / 0 - 20 °C / Inert atmosphere

2: diisobutylaluminium hydride / dichloromethane; toluene / 1 h / -78 °C / Inert atmosphere

3: acetonitrile / 0.33 h / Inert atmosphere; Reflux

4: 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; potassium tert-butylate / dichloromethane / 24 h / 20 °C / Reflux; Inert atmosphere

With 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; potassium tert-butylate; sodium; diisobutylaluminium hydride; In dichloromethane; toluene; acetonitrile;

DOI:10.1039/c1ob05854a

upstream raw materials:

methyl 3-(2-methylphenyl)glycidate

2-methylphenyl aldehyde