C₃₇H₃₄F₆N₄O₄

Base Information

• Chemical Name: C₃₇H₃₄F₆N₄O₄
• CAS No.: 1601475-78-8
• Molecular Formula: C₃₇H₃₄F₆N₄O₄
• Molecular Weight: 712.692
• Mol file: 1601475-78-8.mol

Synonyms:

Chemical Property of C₃₇H₃₄F₆N₄O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₃₄F₆N₄O₄

There total 13 articles about C₃₇H₃₄F₆N₄O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H21NO3 (1601476-01-0) → C37H34F6N4O4 (1601475-78-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 0 - 40 °C

2: HATU; N-ethyl-N,N-diisopropylamine

3: hydrogenchloride; water / 1,4-dioxane

4: HATU

With hydrogenchloride; water; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane; 1: |Bargellini Reaction;

DOI:10.1016/j.bmcl.2014.02.055

Reference yield:

C24H26F3NO5 → C37H34F6N4O4 (1601475-78-8)

Guidance literature:

Multi-step reaction with 3 steps

1: HATU; N-ethyl-N,N-diisopropylamine

2: hydrogenchloride; water / 1,4-dioxane

3: HATU

With hydrogenchloride; water; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane;

DOI:10.1016/j.bmcl.2014.02.055

Reference yield:

C16H23NO3 → C37H34F6N4O4 (1601475-78-8)

Guidance literature:

Multi-step reaction with 5 steps

1: Dess-Martin periodane

2: 0 - 40 °C

3: HATU; N-ethyl-N,N-diisopropylamine

4: hydrogenchloride; water / 1,4-dioxane

5: HATU

With hydrogenchloride; water; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane; 2: |Bargellini Reaction;

DOI:10.1016/j.bmcl.2014.02.055

upstream raw materials:

C₁₆H₂₁NO₃

4-(trifluoromethyl)nicotinic acid

C₁₁H₁₉NO₃

(2S,4R)-1-(tert-butoxycarbonyl)-4-phenyl-2-pyrrolidinecarboxylic acid