Technology Process of C22H22O5
There total 9 articles about C22H22O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 8 h / 0 - 20 °C / Inert atmosphere
2.1: n-butyllithium / hexane; diethyl ether / 3 h / 0 - 20 °C / Inert atmosphere
2.2: 0.17 h / 0 °C / Inert atmosphere
3.1: montmorillonite K-10 / benzene / 1 h / 20 °C
4.1: potassium carbonate / acetone / 4.5 h / 0 - 20 °C
5.1: tetrakis(triphenylphosphine) palladium(0); potassium phosphate / water; 1,2-dimethoxyethane / 3.5 h / Reflux
With
potassium phosphate; tetrakis(triphenylphosphine) palladium(0); n-butyllithium; sodium hydride; potassium carbonate;
In
1,2-dimethoxyethane; diethyl ether; hexane; water; N,N-dimethyl-formamide; acetone; mineral oil; benzene;
5.1: |Suzuki Coupling;
DOI:10.1021/ja311902f
- Guidance literature:
-
Multi-step reaction with 3 steps
1: montmorillonite K-10 / benzene / 1 h / 20 °C
2: potassium carbonate / acetone / 4.5 h / 0 - 20 °C
3: tetrakis(triphenylphosphine) palladium(0); potassium phosphate / water; 1,2-dimethoxyethane / 3.5 h / Reflux
With
potassium phosphate; tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
1,2-dimethoxyethane; water; acetone; benzene;
3: |Suzuki Coupling;
DOI:10.1021/ja311902f
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / hexane; diethyl ether / 3 h / 0 - 20 °C / Inert atmosphere
1.2: 0.17 h / 0 °C / Inert atmosphere
2.1: montmorillonite K-10 / benzene / 1 h / 20 °C
3.1: potassium carbonate / acetone / 4.5 h / 0 - 20 °C
4.1: tetrakis(triphenylphosphine) palladium(0); potassium phosphate / water; 1,2-dimethoxyethane / 3.5 h / Reflux
With
potassium phosphate; tetrakis(triphenylphosphine) palladium(0); n-butyllithium; potassium carbonate;
In
1,2-dimethoxyethane; diethyl ether; hexane; water; acetone; benzene;
4.1: |Suzuki Coupling;
DOI:10.1021/ja311902f