oleoyl alanine

Base Information

• Chemical Name: oleoyl alanine
• CAS No.: 136897-50-2
• Molecular Formula: C₂₁H₃₉NO₃
• Molecular Weight: 353.546
• Mol file: 136897-50-2.mol

Synonyms:

Chemical Property of oleoyl alanine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of oleoyl alanine

There total 9 articles about oleoyl alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl (2R)-2-[[(Z)-octadec-9-enoyl]amino]propanoate (1392197-62-4) → (2R)-2-[[(Z)-octadec-9-enoyl]amino]propanoic acid (136897-50-2)

Guidance literature:

methyl (2R)-2-[[(Z)-octadec-9-enoyl]amino]propanoate; With water; sodium hydroxide; In methanol; at 20 ℃; for 4h;

With hydrogenchloride; In methanol; water;

DOI:10.1039/c2nj20976d

Reference yield: 76.0%

(Z)-9-octadecenoyl chloride (112-77-6) + L-alanin (56-41-7,25191-17-7,18875-37-1) → N-oleoyl-L-alanine (136897-50-2)

Guidance literature:

(Z)-9-octadecenoyl chloride; L-alanin; With sodium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 12h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; pH=2; Inert atmosphere;

DOI:10.1021/jo301659c

Reference yield: 51.0%

methyl (2S)-2-[[(Z)-octadec-9-enoyl]amino]propanoate → N-oleoyl-L-alanine (136897-50-2)

Guidance literature:

With water; sodium hydroxide; In ethanol; at 40 ℃; for 3h;

DOI:10.1021/acs.jmedchem.8b01775

upstream raw materials:

cis-Octadecenoic acid

(Z)-9-octadecenoyl chloride

L-alanin

methyl (2R)-2-[[(Z)-octadec-9-enoyl]amino]propanoate