(2S,3S)-(3-nonyloxiran-2-yl)methanol

Base Information

• Chemical Name: (2S,3S)-(3-nonyloxiran-2-yl)methanol
• CAS No.: 107796-97-4
• Molecular Formula: C₁₂H₂₄O₂
• Molecular Weight: 200.321
• Mol file: 107796-97-4.mol

Synonyms:

Chemical Property of (2S,3S)-(3-nonyloxiran-2-yl)methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S)-(3-nonyloxiran-2-yl)methanol

There total 6 articles about (2S,3S)-(3-nonyloxiran-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(2S,3S,4Z)-1-benzyloxy-2,3-epoxydodec-4-ene → (2S,3S)-(3-nonyloxiran-2-yl)methanol (107796-97-4,246545-38-0)

Guidance literature:

With hydrogen; palladium dihydroxide; In methanol; ethyl acetate; at 20 ℃; for 12h; under 4137.29 Torr;

DOI:10.1002/ejoc.200700449

Reference yield: 91.0%

(2E)-dodec-2-en-1-ol (22104-81-0,69064-36-4,69064-37-5) → (2S,3S)-(3-nonyloxiran-2-yl)methanol (107796-97-4,246545-38-0)

Guidance literature:

(2E)-dodec-2-en-1-ol; With titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; In dichloromethane; for 0.5h; Molecular sieve; Inert atmosphere;

With tert.-butylhydroperoxide; In dichloromethane; toluene; at -25 - 0 ℃; for 24h; Molecular sieve; Inert atmosphere;

DOI:10.1016/j.ejmech.2016.04.073

Reference yield:

caprinaldehyde (112-31-2) → (2S,3S)-(3-nonyloxiran-2-yl)methanol (107796-97-4,246545-38-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 12 h / 20 °C

2.1: diisobutylaluminium hydride / dichloromethane; toluene / 1 h / -78 - 20 °C

3.1: titanium(IV) isopropylate; L-(+)-diisopropyl tartrate / dichloromethane / 0.5 h / Molecular sieve; Inert atmosphere

3.2: 24 h / -25 - 0 °C / Molecular sieve; Inert atmosphere

With titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane; toluene; 1.1: |Wittig Olefination;

DOI:10.1016/j.ejmech.2016.04.073

upstream raw materials:

(2E)-dodec-2-en-1-ol

caprinaldehyde

1-Decanol

ethyl (E)-dodec-2-enoate