(αS)-4-methoxy-α-O-(4-methoxybenzoyl)-2',4'-di-O-methoxymethyldihydrochalcone

Base Information

• Chemical Name: (αS)-4-methoxy-α-O-(4-methoxybenzoyl)-2',4'-di-O-methoxymethyldihydrochalcone
• CAS No.: 114107-29-8
• Molecular Formula: C₂₈H₃₀O₉
• Molecular Weight: 510.541
• Mol file: 114107-29-8.mol

Synonyms:

Chemical Property of (αS)-4-methoxy-α-O-(4-methoxybenzoyl)-2',4'-di-O-methoxymethyldihydrochalcone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (αS)-4-methoxy-α-O-(4-methoxybenzoyl)-2',4'-di-O-methoxymethyldihydrochalcone

There total 2 articles about (αS)-4-methoxy-α-O-(4-methoxybenzoyl)-2',4'-di-O-methoxymethyldihydrochalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2',4'-bis(methoxymethoxy)acetophenone (6515-05-5) → (αS)-4-methoxy-α-O-(4-methoxybenzoyl)-2',4'-di-O-methoxymethyldihydrochalcone (114107-29-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 74 percent

2: 43 percent / NaOH, 30percent H₂O₂ / poly-L-alanine / CCl₄ / 72 h

3: 50 percent / H₂ / Pd-BaSO₄ / methanol / 4 h

4: pyridine / 14 h / 40 °C

With pyridine; sodium hydroxide; hydrogen; dihydrogen peroxide; poly-L-alanine; palladium on barium sulfate; In methanol; tetrachloromethane;

DOI:10.1016/S0040-4020(01)86778-8

Reference yield:

4-methoxy-2',4'-di-O-methoxymethylchalcone epoxide (114107-23-2,114246-90-1) → (αS)-4-methoxy-α-O-(4-methoxybenzoyl)-2',4'-di-O-methoxymethyldihydrochalcone (114107-29-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / H₂ / Pd-BaSO₄ / methanol / 4 h

2: pyridine / 14 h / 40 °C

With pyridine; hydrogen; palladium on barium sulfate; In methanol;

DOI:10.1016/S0040-4020(01)86778-8

upstream raw materials:

2',4'-bis(methoxymethoxy)acetophenone

4-methoxy-2',4'-di-O-methoxymethylchalcone epoxide