Technology Process of (3aR,4R,6R,6aR)-4-Methoxy-2,2-dimethyl-6-[(Z)-3-((R)-4-methyl-cyclohex-3-enyl)-but-1-enyl]-tetrahydro-furo[3,4-d][1,3]dioxole
There total 4 articles about (3aR,4R,6R,6aR)-4-Methoxy-2,2-dimethyl-6-[(Z)-3-((R)-4-methyl-cyclohex-3-enyl)-but-1-enyl]-tetrahydro-furo[3,4-d][1,3]dioxole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) borane-THF complex, 2.) 3 M aq. NaOH, 30percent H2O2 / 1.) THF, 0 deg C, 5 h, 2.) THF, 50 deg C, 3 h
2: 1.) triphenylphosphine (TPP), diethyl azodicarboxylate, 2.) MeI / 1.) THF, RT, 5 min, 2.) THF, 0.5 h
3: 12 h / 110 °C
4: 1.) LHMDS / 1.) THF, -15 deg C, 15 min, 2.) a) THF, 0 deg C, 5 min, b) RT, 15 min
With
sodium hydroxide; borane-THF; dihydrogen peroxide; triphenylphosphine; lithium hexamethyldisilazane; diethylazodicarboxylate; methyl iodide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) triphenylphosphine (TPP), diethyl azodicarboxylate, 2.) MeI / 1.) THF, RT, 5 min, 2.) THF, 0.5 h
2: 12 h / 110 °C
3: 1.) LHMDS / 1.) THF, -15 deg C, 15 min, 2.) a) THF, 0 deg C, 5 min, b) RT, 15 min
With
triphenylphosphine; lithium hexamethyldisilazane; diethylazodicarboxylate; methyl iodide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 12 h / 110 °C
2: 1.) LHMDS / 1.) THF, -15 deg C, 15 min, 2.) a) THF, 0 deg C, 5 min, b) RT, 15 min
With
lithium hexamethyldisilazane;
