Technology Process of 12-benzyl-5,5a,6,7,8,9-hexahydro-5,9a-iminoethano-4H-naphtho<2,1-b>thiophene
There total 9 articles about 12-benzyl-5,5a,6,7,8,9-hexahydro-5,9a-iminoethano-4H-naphtho<2,1-b>thiophene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 94 percent / potassium carbonate, / benzene / 1 h / Ambient temperature
2: phosphorus pentoxide / benzene / 1.17 h / Heating
3: 55 percent / formamide / 3 h / Heating
4: 20 percent / KOH / ethanol / 45 h / Heating
5: 83 percent / potassium carbonate / benzene / 7 h / Heating
6: 43 percent / 48percent hydrobromic acid / 15 h / Heating
With
phosphorus pentaoxide; potassium hydroxide; hydrogen bromide; potassium carbonate;
In
ethanol; formamide; benzene;
DOI:10.1002/jhet.5570200608
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 55 percent / formamide / 3 h / Heating
2: 20 percent / KOH / ethanol / 45 h / Heating
3: 83 percent / potassium carbonate / benzene / 7 h / Heating
4: 43 percent / 48percent hydrobromic acid / 15 h / Heating
With
potassium hydroxide; hydrogen bromide; potassium carbonate;
In
ethanol; formamide; benzene;
DOI:10.1002/jhet.5570200608
