6'-Epipravastatin

Base Information

Chemical Name:6'-Epipravastatin
CAS No.:250737-12-3
Molecular Formula:C₂₃H₃₆O₇
Molecular Weight:424.535
Hs Code.:
UNII:R76ZW7E32P
Nikkaji Number:J448.313H
Wikidata:Q27287878
ChEMBL ID:CHEMBL3544781
Mol file:250737-12-3.mol

Synonyms:6'-Epipravastatin;250737-12-3;UNII-R76ZW7E32P;R76ZW7E32P;Pravastatin sodium specified impurity A [EP];(3R,5R)-3,5-Dihydroxy-7-((1S,2S,6R,8S,8aR)-6-hydroxy-2-methyl-8-(((2S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid;(3R,5R)-7-[(1S,2S,6R,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid;Pravastatin sodium impurity, 6'-epipravastatin- [USP];1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, (betaR,deltaR,1S,2S,6R,8S,8aR)-;CHEMBL3544781;SCHEMBL14430866;PRAVASTATIN SODIUM IMPURITY A [EP IMPURITY];Q27287878;PRAVASTATIN SODIUM IMPURITY, 6'-EPIPRAVASTATIN- [USP IMPURITY];1-NAPHTHALENEHEPTANOIC ACID, 1,2,6,7,8,8A-HEXAHYDRO-.BETA.,.DELTA.,6-TRIHYDROXY-2-METHYL-8-((2S)-2-METHYL-1-OXOBUTOXY)-, (.BETA.R,.DELTA.R,1S,2S,6R,8S,8AR)-

Suppliers and Price of 6'-Epipravastatin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Pravastatin impurity A European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Pravastatin impurity A European Pharmacopoeia (EP) Reference Standard
y0000223
$ 190.00

Total 1 raw suppliers

Chemical Property of 6'-Epipravastatin

Chemical Property:

Boiling Point:634.5±55.0 °C(Predicted)
PKA:4.31±0.10(Predicted)
Density:1.21±0.1 g/cm3(Predicted)
XLogP3:1.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:424.24610348
Heavy Atom Count:30
Complexity:656

Purity/Quality:

99% ^*data from raw suppliers

Pravastatin impurity A European Pharmacopoeia (EP) Reference Standard ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)O
Isomeric SMILES:CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O

Technology Process of 6'-Epipravastatin

There total 7 articles about 6'-Epipravastatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.4%

: 73573-88-3,58948-09-7
mevastatin

: 81093-37-0,81131-74-0,250737-12-3
pravastatin

Guidance literature:

Reference yield:

: 81131-70-6,81176-41-2,124917-23-3
pravastatin sodium salt

: 81093-37-0,81131-74-0,250737-12-3
pravastatin

Guidance literature:: With hydrogenchloride; In water; pH=4.0;

Reference yield:

: Compactin sodium salt

: 81093-37-0,81131-74-0,250737-12-3
pravastatin

Guidance literature:: With carbenicillin; isopropyl β-D-thiogalactopyranoside; glycerol; at 28 ℃; for 24h; pH=7.4; aq. phosphate buffer;
DOI:10.1271/bbb.80627