4-[5-(3-Methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine

Base Information

Chemical Name:4-[5-(3-Methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS No.:331989-56-1
Molecular Formula:C₁₄H₁₁N₃O₂
Molecular Weight:253.26
Hs Code.:
DSSTox Substance ID:DTXSID901326094
ChEMBL ID:CHEMBL1505703
Mol file:331989-56-1.mol

Synonyms:4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine;331989-56-1;5-(3-methoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole;Oprea1_389692;Oprea1_780618;MLS001165261;CHEMBL1505703;DTXSID901326094;HMS2854N11;methyl 3-[3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]phenyl ether;CCG-20584;STK321240;AKOS000595441;8K-570S;SMR000549732;CS-0327785;SR-01000496569;SR-01000496569-1;5-(3-Methoxyphenyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole

Suppliers and Price of 4-[5-(3-Methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL-3-[3-(4-PYRIDINYL)-1,2,4-OXADIAZOL-5-YL]PHENYL ETHER 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
METHYL-3-[3-(4-PYRIDINYL)-1,2,4-OXADIAZOL-5-YL]PHENYL ETHER 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
METHYL-3-[3-(4-PYRIDINYL)-1,2,4-OXADIAZOL-5-YL]PHENYL ETHER 95.00%
1MG
$ 647.61

Total 1 raw suppliers

Chemical Property of 4-[5-(3-Methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:253.085126602
Heavy Atom Count:19
Complexity:284

Purity/Quality:

99% ^*data from raw suppliers

METHYL-3-[3-(4-PYRIDINYL)-1,2,4-OXADIAZOL-5-YL]PHENYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2=NC(=NO2)C3=CC=NC=C3

Technology Process of 4-[5-(3-Methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine

There total 2 articles about 4-[5-(3-Methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1594-57-6,849833-58-5
pyridine-4-carboxamidoxime

: 1711-05-3
m-anisoyl chloride

: 331989-56-1
3-(4′-pyridyl)-5-(3′-methoxyphenyl)-1,2,4-oxadiazole

Guidance literature:: With pyridine; In toluene; Reflux;
DOI:10.1016/j.ejmech.2016.06.048

Reference yield:

: 100-48-1
pyridine-4-carbonitrile

: 331989-56-1
3-(4′-pyridyl)-5-(3′-methoxyphenyl)-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 8 h / Reflux

2: pyridine / toluene / Reflux

With pyridine; hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; toluene;
DOI:10.1016/j.ejmech.2016.06.048