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(R)-3,3-Dimethyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyric acid methyl ester

Base Information Edit
  • Chemical Name:(R)-3,3-Dimethyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyric acid methyl ester
  • CAS No.:104267-14-3
  • Molecular Formula:C17H22F3NO4
  • Molecular Weight:361.361
  • Hs Code.:
  • Mol file:104267-14-3.mol
(R)-3,3-Dimethyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyric acid methyl ester

Synonyms:

Suppliers and Price of (R)-3,3-Dimethyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyric acid methyl ester
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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of (R)-3,3-Dimethyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyric acid methyl ester Edit
Chemical Property:
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Safty Information:
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Technology Process of (R)-3,3-Dimethyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyric acid methyl ester

There total 11 articles about (R)-3,3-Dimethyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 3 steps
1: LDA / tetrahydrofuran; CH2Cl2 / -78 °C
2: 51 percent / tetrahydrofuran; hexane / 50 h / -50 °C
With lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1016/S0040-4020(01)86058-0
Guidance literature:
Multi-step reaction with 4 steps
1: 92 percent / n-BuLi / tetrahydrofuran / 1.) -78 degC, 20 min.; 2.) from -78 to 25 degC, 1 h.
2: LDA / tetrahydrofuran; CH2Cl2 / -78 °C
3: 51 percent / tetrahydrofuran; hexane / 50 h / -50 °C
With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1016/S0040-4020(01)86058-0
Guidance literature:
Multi-step reaction with 4 steps
1: 92 percent / n-BuLi / tetrahydrofuran / 1.) -78 degC, 20 min.; 2.) from -78 to 25 degC, 1 h.
2: LDA / tetrahydrofuran; CH2Cl2 / -78 °C
3: 51 percent / tetrahydrofuran; hexane / 50 h / -50 °C
With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1016/S0040-4020(01)86058-0
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