Technology Process of (E)-2,3-dimethyl-6-(2-styrylphenyl)pyridine
There total 3 articles about (E)-2,3-dimethyl-6-(2-styrylphenyl)pyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver(I) acetate;
In
acetic acid; 1,2-dichloro-ethane;
at 85 ℃;
for 14h;
regioselective reaction;
Inert atmosphere;
DOI:10.1021/ja3104389
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydroxylamine hydrochloride; sodium carbonate / methanol / 1 h / 65 °C / Inert atmosphere
2: triethylamine / dichloromethane / 0 °C / Inert atmosphere
3: silver(I) acetate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer / 1,2-dichloro-ethane; acetic acid / 14 h / 85 °C / Inert atmosphere
With
dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; hydroxylamine hydrochloride; silver(I) acetate; sodium carbonate; triethylamine;
In
methanol; dichloromethane; acetic acid; 1,2-dichloro-ethane;
DOI:10.1021/ja3104389
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 0 °C / Inert atmosphere
2: silver(I) acetate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer / 1,2-dichloro-ethane; acetic acid / 14 h / 85 °C / Inert atmosphere
With
dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver(I) acetate; triethylamine;
In
dichloromethane; acetic acid; 1,2-dichloro-ethane;
DOI:10.1021/ja3104389
