Spiro[cyclohexane-1,3'-indolin]-2'-one

Base Information

Chemical Name:Spiro[cyclohexane-1,3'-indolin]-2'-one
CAS No.:4933-14-6
Molecular Formula:C13H15 N O
Molecular Weight:201.26
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30512368
Nikkaji Number:J465.528A
Wikidata:Q82371576
Mol file:4933-14-6.mol

Synonyms:4933-14-6;Spiro[cyclohexane-1,3'-indolin]-2'-one;Spiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one;Spiro[cyclohexane-1,3'-indol]-2'(1'H)-one;spiro[1H-indole-3,1'-cyclohexane]-2-one;1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one;Spiro[cyclohexane-1,3//'-indol]-2//'(1//'H)-one;SCHEMBL1223213;DTXSID30512368;LLHRWZOIAVWPKH-UHFFFAOYSA-N;MFCD11935809;SB64464;CS-0217609;EN300-79333;AN-584/43460758;spiro[cyclohexane-1,3'-[3h]indol]-2' (1'h)-one;spiro[cyclohexane-1,3'-[3H]indol]-2'-(1'H)one;Spiro [cyclohexane-1,3'-[3H]indol]-2'-(1'H) one;spiro[cyclohexane-1,3'-[3H]indol]-2'-(1'H)-one;Z1210584851;1',3'-dihydrospiro[cyclohexane-1,3'-(2'H)-indole]-2'-one;SPIRO[CYCLOHEXANE-1,3'-[3H]INDOL]-2'(1'H)-ONE,95+%

Suppliers and Price of Spiro[cyclohexane-1,3'-indolin]-2'-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Spiro[cyclohexane-1,3''-indol]-2''(1''H)-one
10mg
$ 45.00

Crysdot
Spiro[cyclohexane-1,3'-indolin]-2'-one 95+%
1g
$ 608.00

Chemenu
spiro[cyclohexane-1,3''-indolin]-2''-one 95%
1g
$ 574.00

Alichem
Spiro[cyclohexane-1,3'-indolin]-2'-one
1g
$ 787.50

Total 6 raw suppliers

Chemical Property of Spiro[cyclohexane-1,3'-indolin]-2'-one

Chemical Property:

Boiling Point:388.107oC at 760 mmHg
Flash Point:231.585oC
PSA：29.10000
Density:1.168g/cm3
LogP:2.97860
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:201.115364102
Heavy Atom Count:15
Complexity:268

Purity/Quality:

99% ^*data from raw suppliers

Spiro[cyclohexane-1,3''-indol]-2''(1''H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2(CC1)C3=CC=CC=C3NC2=O

Technology Process of Spiro[cyclohexane-1,3'-indolin]-2'-one

There total 49 articles about Spiro[cyclohexane-1,3'-indolin]-2'-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 106795-71-5
1-(o-bromophenyl)cyclohexane-1-carboxamide

: 4933-14-6
spiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one

Guidance literature:: With copper(I) oxide; 1,2-diamino-benzene; sodium t-butanolate; In tert-butyl alcohol; at 100 ℃; for 24h; Sealed tube;
DOI:10.1016/j.tetlet.2012.12.082

Reference yield: 87.0%

: 82757-23-1
2'-amino

: 4933-14-6
spiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one

Guidance literature:: With hydrogenchloride; In chloroform; for 0.166667h; Ambient temperature;

Reference yield: 86.0%

: 59-48-3
2-oxoindole

: 111-24-0
1,5-dibromo-pentane

: 4933-14-6
spiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one

Guidance literature:: 2-oxoindole; With lithium hexamethyldisilazane; In tetrahydrofuran; at -74 - -50 ℃; for 0.5h; Inert atmosphere;

1,5-dibromo-pentane; In tetrahydrofuran; at 20 ℃; for 10h; Inert atmosphere; Reflux;
DOI:10.1021/jm4013906