H-LEU-HIS-OH

Base Information

• Chemical Name: H-LEU-HIS-OH
• CAS No.: 38062-72-5
• Molecular Formula: C₁₂H₂₀N₄O₃
• Molecular Weight: 268.316
• Mol file: 38062-72-5.mol

Synonyms:Histidine,N-L-leucyl- (6CI); L-Histidine, N-L-leucyl-; 1578: PN: US20060223088 SEQID:1588 claimed protein; 1588: PN: WO02102994 SEQID: 1588 claimed protein; 2494:PN: EP2071334 SEQID: 2611 claimed protein; 2494: PN: WO2009077864 SEQID: 2611claimed protein; 687: PN: WO03004622 SEQID: 687 claimed protein;L-Leucyl-L-histidine; NSC 374664

Chemical Property of H-LEU-HIS-OH

Chemical Property:

• Vapor Pressure: 1.97E-15mmHg at 25°C
• Boiling Point: 603.9°C at 760 mmHg
• PKA: 2.87±0.10(Predicted)
• Flash Point: 319°C
• PSA: 121.10000
• Density: 1.249g/cm³
• LogP: 0.98620
• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

LEU-HIS-OH 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-LEU-HIS-OH

There total 5 articles about H-LEU-HIS-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nα-((Ξ)-2-bromo-4-methyl-valeryl)-L-histidine-methyl ester (910890-97-0) → Nα-Ξ-leucyl-L-histidine (38062-71-4,38062-72-5,97371-26-1,107610-16-2)

Guidance literature:

With ammonia;

Reference yield:

2-bromo-4-methylpentanoyl chloride (28659-88-3,59960-79-1,104420-63-5) → Nα-Ξ-leucyl-L-histidine (38062-71-4,38062-72-5,97371-26-1,107610-16-2)

Guidance literature:

Multi-step reaction with 2 steps

2: NH₃

With ammonia;

Reference yield:

L-Histidine methyl ester (1499-46-3) → Nα-Ξ-leucyl-L-histidine (38062-71-4,38062-72-5,97371-26-1,107610-16-2)

Guidance literature:

Multi-step reaction with 2 steps

2: NH₃

With ammonia;

upstream raw materials:

N^α-((Ξ)-2-bromo-4-methyl-valeryl)-L-histidine

N^α-((Ξ)-2-bromo-4-methyl-valeryl)-L-histidine-methyl ester

2-bromo-4-methylpentanoyl chloride

L-Histidine methyl ester

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