(E)-2-(Hydroxyimino)-3-morpholinopropiophenon

Base Information

• Chemical Name: (E)-2-(Hydroxyimino)-3-morpholinopropiophenon
• CAS No.: 100616-18-0
• Molecular Formula: C₁₃H₁₆N₂O₃
• Molecular Weight: 248.282
• Mol file: 100616-18-0.mol

Synonyms:

Chemical Property of (E)-2-(Hydroxyimino)-3-morpholinopropiophenon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-(Hydroxyimino)-3-morpholinopropiophenon

There total 6 articles about (E)-2-(Hydroxyimino)-3-morpholinopropiophenon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-(morpholinomethyl)morpholine (5625-90-1) + E-isonitrosoacetophenone (532-54-7,22668-53-7) → (E)-2-(Hydroxyimino)-3-morpholinopropiophenon (100616-18-0)

Guidance literature:

In 1,4-dioxane; for 0.666667h; Heating;

DOI:10.1515/znb-1999-0511

Reference yield:

3-morpholino-1-phenylpropan-1-one hydrochloride (1020-16-2) → (E)-2-(Hydroxyimino)-3-morpholinopropiophenon (100616-18-0)

Guidance literature:

With hydrogenchloride; methanol; nitrous acid isobutyl ester;

DOI:10.1021/ja01592a079

Reference yield:

3-chloropropiophenone (936-59-4) → (E)-2-(Hydroxyimino)-3-morpholinopropiophenon (100616-18-0)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl; ether benzene

With hydrogenchloride; ether benzene;

upstream raw materials:

morpholine

3-chloro-1-phenyl-propane-1,2-dione-2-oxime

3-morpholino-1-phenylpropan-1-one hydrochloride

4-(morpholinomethyl)morpholine

Downstream raw materials:

1-hydroxy-3-morpholin-4-yl-1-phenyl-propan-2-one oxime