Technology Process of 6-aminobenzyl-3-methyl-5-nitropyridine
There total 1 articles about 6-aminobenzyl-3-methyl-5-nitropyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate;
In
toluene;
at 100 ℃;
DOI:10.1016/j.bmcl.2012.03.075
- Guidance literature:
-
With
palladium 10% on activated carbon; ammonium acetate;
In
ethanol;
at 100 ℃;
DOI:10.1016/j.bmcl.2012.03.075
- Guidance literature:
-
Multi-step reaction with 10 steps
1: palladium 10% on activated carbon; ammonium acetate / ethanol / 100 °C
2: sodium sulfate / dichloromethane / -20 °C
3: boron trifluoride diethyl etherate / -20 - -10 °C
4: pyridine / 0 - 20 °C
5: hydrogenchloride / water / 80 °C
6: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 20 °C
7: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C
8: sodium azide; triethylamine / toluene / 110 °C
9: ammonium cerium (IV) nitrate; potassium carbonate
10: palladium 10% on activated carbon; hydrogen / methanol
With
pyridine; hydrogenchloride; sodium azide; ammonium cerium (IV) nitrate; palladium 10% on activated carbon; boron trifluoride diethyl etherate; ammonium acetate; hydrogen; sodium tris(acetoxy)borohydride; potassium carbonate; sodium sulfate; triethylamine; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; 1,2-dichloro-ethane; toluene;
DOI:10.1016/j.bmcl.2012.03.075
