<(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat

Base Information

• Chemical Name: <(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat
• CAS No.: 131570-06-4
• Molecular Formula: C₂₄H₂₄O₈
• Molecular Weight: 440.45
• Mol file: 131570-06-4.mol

Synonyms:

Chemical Property of <(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat

There total 4 articles about <(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid (2R,4aR,5aS,11aS,12S,12aR)-6-hydroxy-5a-nitro-2-phenyl-4a,5a,6,11a,12,12a-hexahydro-4H-1,3,5,11-tetraoxa-naphthacen-12-yl ester (131570-02-0,131615-91-3) → <(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat (131570-06-4,131615-95-7,131615-96-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / Bu3SnH, α,α'-azoisobutyronitrile / benzene / 4 h / Heating

2: 54 percent / MnO₂ / CH₂Cl₂ / 16 h / Ambient temperature

3: 1) NaBH₄, 2) pyridine, DMAP / 1) ethanol, 0 deg C, 1 h, 2) THF, r.t., 1 h

With pyridine; dmap; manganese(IV) oxide; sodium tetrahydroborate; azobisisobutyronitrile; tri-n-butyl-tin hydride; In dichloromethane; benzene;

DOI:10.1002/hlca.19900730715

Reference yield:

Acetic acid (2R,4aR,5aS,6R,11aR,12R,12aR)-6-hydroxy-2-phenyl-4a,5a,6,11a,12,12a-hexahydro-4H-1,3,5,11-tetraoxa-naphthacen-12-yl ester (131570-05-3,131615-93-5,131615-94-6) → <(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat (131570-06-4,131615-95-7,131615-96-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 54 percent / MnO₂ / CH₂Cl₂ / 16 h / Ambient temperature

2: 1) NaBH₄, 2) pyridine, DMAP / 1) ethanol, 0 deg C, 1 h, 2) THF, r.t., 1 h

With pyridine; dmap; manganese(IV) oxide; sodium tetrahydroborate; In dichloromethane;

DOI:10.1002/hlca.19900730715

Reference yield:

Acetic acid (2R,4aR,5aS,6S,11aR,12R,12aR)-6-hydroxy-2-phenyl-4a,5a,6,11a,12,12a-hexahydro-4H-1,3,5,11-tetraoxa-naphthacen-12-yl ester (131570-05-3,131615-93-5,131615-94-6) → <(2R,4aR,5aR,6S,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-6,12-diyl>diacetat (131570-06-4,131615-95-7,131615-96-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / MnO₂ / CH₂Cl₂ / Ambient temperature

2: 1) NaBH₄, 2) pyridine, DMAP / 1) ethanol, 0 deg C, 1 h, 2) THF, r.t., 1 h

With pyridine; dmap; manganese(IV) oxide; sodium tetrahydroborate; In dichloromethane;

DOI:10.1002/hlca.19900730715

upstream raw materials:

acetic anhydride

<(2R,4aR,5aR,6R,11aR,12R,12aR)-4a,5a,6,11a,12,12a-hexahydro-6-oxo-2-phenyl-2H,4H-<1,3>dioxino<4',5':5,6>pyrano<3,2-b><1>benzopyran-12-yl>-acetate

Acetic acid (2R,4aR,5aS,6R,11aR,12R,12aR)-6-hydroxy-2-phenyl-4a,5a,6,11a,12,12a-hexahydro-4H-1,3,5,11-tetraoxa-naphthacen-12-yl ester

Acetic acid (2R,4aR,5aS,6S,11aR,12R,12aR)-6-hydroxy-2-phenyl-4a,5a,6,11a,12,12a-hexahydro-4H-1,3,5,11-tetraoxa-naphthacen-12-yl ester