N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride

Base Information

• Chemical Name: N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride
• CAS No.: 102104-90-5
• Molecular Formula: C₃₂H₅₄N₄O₆S₂*4ClH
• Molecular Weight: 800.78
• Mol file: 102104-90-5.mol

Synonyms:

Chemical Property of N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride

There total 5 articles about N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

N,N'-bis<6-<2-hydroxy-2-(3,4-bis(methoxymethoxy)phenyl)ethylamino>hexyl>cystamine (102104-83-6) → N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride (102104-90-5)

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane; for 20h; Ambient temperature;

DOI:10.1002/jhet.5570220326

Reference yield:

3,4-bis-methoxymethoxy-benzaldehyde (6515-06-6) → N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride (102104-90-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 99 percent / aq. sodium hydroxide (50 percent), tetrabuthylammonium bromide / CH₂Cl₂ / 96 h / 50 °C

2: 75 percent / propan-2-ol / 22 h / Heating

3: 56 percent / iodine (0.1 N)-potassium iodide (2.5 percent), hydrochloric acid (2N) / ethanol / 12 h / Ambient temperature

4: 60 percent / hydrogen chloride / methanol; CH₂Cl₂ / 20 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; tetrabutylammomium bromide; iodine; potassium iodide; In methanol; ethanol; dichloromethane; isopropyl alcohol;

DOI:10.1002/jhet.5570220326

Reference yield:

2-<3,4-bis(methoxymethoxy)phenyl>oxirane (102104-62-1) → N,N'-bis<6<<2-hydroxy-2-(3,4-dihydroxyphenyl)ethyl>amino>hexyl>cystamine hydrochloride (102104-90-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / propan-2-ol / 22 h / Heating

2: 56 percent / iodine (0.1 N)-potassium iodide (2.5 percent), hydrochloric acid (2N) / ethanol / 12 h / Ambient temperature

3: 60 percent / hydrogen chloride / methanol; CH₂Cl₂ / 20 h / Ambient temperature

With hydrogenchloride; iodine; potassium iodide; In methanol; ethanol; dichloromethane; isopropyl alcohol;

DOI:10.1002/jhet.5570220326

upstream raw materials:

N,N'-bis<6-<2-hydroxy-2-(3,4-bis(methoxymethoxy)phenyl)ethylamino>hexyl>cystamine

3,4-bis-methoxymethoxy-benzaldehyde

2-<3,4-bis(methoxymethoxy)phenyl>oxirane

3-(6-aminohexyl)-1,3-thiazolidine