2-PyrrolidinecarboxaMide, N-[(2S)-2-hydroxy-2-phenylethyl]-4-(MethoxyiMino)-1-[(2'-Methyl[1,1'-biphenyl]-4-yl)carbonyl]-, (2S,4Z)-

Base Information

• Chemical Name: 2-PyrrolidinecarboxaMide, N-[(2S)-2-hydroxy-2-phenylethyl]-4-(MethoxyiMino)-1-[(2'-Methyl[1,1'-biphenyl]-4-yl)carbonyl]-, (2S,4Z)-
• CAS No.: 364071-17-0
• Molecular Formula: C₂₈H₂₉N₃O₄
• Molecular Weight: 471.556
• Mol file: 364071-17-0.mol

Synonyms:

Chemical Property of 2-PyrrolidinecarboxaMide, N-[(2S)-2-hydroxy-2-phenylethyl]-4-(MethoxyiMino)-1-[(2'-Methyl[1,1'-biphenyl]-4-yl)carbonyl]-, (2S,4Z)-

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

OT-Rantagonist1 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-PyrrolidinecarboxaMide, N-[(2S)-2-hydroxy-2-phenylethyl]-4-(MethoxyiMino)-1-[(2'-Methyl[1,1'-biphenyl]-4-yl)carbonyl]-, (2S,4Z)-

There total 6 articles about 2-PyrrolidinecarboxaMide, N-[(2S)-2-hydroxy-2-phenylethyl]-4-(MethoxyiMino)-1-[(2'-Methyl[1,1'-biphenyl]-4-yl)carbonyl]-, (2S,4Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C25H28N2O5 + (S)-2-Amino-1-phenyl-1-ethanol (56613-81-1,1936-63-6) → C28H29N3O4 (364076-14-2,364071-17-0)

Guidance literature:

In dichloromethane; at 5 - 25 ℃;

Reference yield:

(2S,4E2)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid + 4-(2-methylphenyl)benzoic acid (5748-43-6) + (R)-2-Amino-1-phenylethanol (2549-14-6,1936-63-6) → N-[(2R)-2-hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide (364071-17-0)

Guidance literature:

Reference yield:

(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid + 4-(2-methylphenyl)benzoic acid (5748-43-6) + 2-Amino-1-phenylethanol (7568-93-6,1936-63-6) → N-[(2RS)-2-hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide (364071-17-0)

Guidance literature:

upstream raw materials:

4-(2-methylphenyl)benzoic acid

(R)-2-Amino-1-phenylethanol

(S)-2-Amino-1-phenyl-1-ethanol

2-Amino-1-phenylethanol