C₃₉H₅₅⁽²⁾H₃O₇S

Base Information

• Chemical Name: C₃₉H₅₅⁽²⁾H₃O₇S
• CAS No.: 1316216-53-1
• Molecular Formula: C₃₉H₅₈O₇S
• Molecular Weight: 673.928
• Mol file: 1316216-53-1.mol

Synonyms:

Chemical Property of C₃₉H₅₅⁽²⁾H₃O₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₉H₅₅⁽²⁾H₃O₇S

There total 7 articles about C₃₉H₅₅⁽²⁾H₃O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[26-(2)H3](22E,24R)-6β-methoxy-3α,5-cyclo-24-methyl-5α-cholest-22-ene (1316216-40-6) → C39H55(2)H3O7S (1316216-53-1)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium hexacyanoferrate(III); potassium osmate(VI) dihydrate; hydroquinidine 1,4-phthalazinediyl diether; methanesulfonamide; water; potassium carbonate; tert-butyl alcohol / 336 h / 20 °C

2: pyridine; dmap / 4.5 h / 45 °C

3: water; toluene-4-sulfonic acid / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere

4: pyridine / 20 °C

With pyridine; dmap; potassium osmate(VI) dihydrate; methanesulfonamide; potassium hexacyanoferrate(III); hydroquinidine 1,4-phthalazinediyl diether; water; potassium carbonate; toluene-4-sulfonic acid; tert-butyl alcohol; In 1,4-dioxane;

DOI:10.1002/jlcr.1874

Reference yield:

(22E,24R)-6β-methoxy-3α,5-cyclo-24-methyl-5α-cholest-22-en-26-oic acid ethyl ester (96615-21-3) → C39H55(2)H3O7S (1316216-53-1)

Guidance literature:

Multi-step reaction with 7 steps

1: lithium aluminium deuteride / tetrahydrofuran; diethyl ether / 1.5 h / 20 °C

2: triethylamine / dichloromethane / 4 h / 0 °C

3: lithium aluminium deuteride / tetrahydrofuran; diethyl ether / 4 h / 20 °C

4: potassium hexacyanoferrate(III); potassium osmate(VI) dihydrate; hydroquinidine 1,4-phthalazinediyl diether; methanesulfonamide; water; potassium carbonate; tert-butyl alcohol / 336 h / 20 °C

5: pyridine; dmap / 4.5 h / 45 °C

6: water; toluene-4-sulfonic acid / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere

7: pyridine / 20 °C

With pyridine; dmap; potassium osmate(VI) dihydrate; lithium aluminium deuteride; methanesulfonamide; potassium hexacyanoferrate(III); hydroquinidine 1,4-phthalazinediyl diether; water; potassium carbonate; toluene-4-sulfonic acid; triethylamine; tert-butyl alcohol; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane;

DOI:10.1002/jlcr.1874

Reference yield:

[26-(2)H3](22R,23R,24R)-6β-methoxy-3α,5-cyclo-24-methyl-5α-cholestan-22,23-diol (1316216-52-0) → C39H55(2)H3O7S (1316216-53-1)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine; dmap / 4.5 h / 45 °C

2: water; toluene-4-sulfonic acid / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere

3: pyridine / 20 °C

With pyridine; dmap; water; toluene-4-sulfonic acid; In 1,4-dioxane;

DOI:10.1002/jlcr.1874

upstream raw materials:

[26-(2)H3](22R,23R,24R)-6β-methoxy-3α,5-cyclo-24-methyl-5α-cholestan-22,23-diol

[26-(2)H3](22R,23R,24R)-6β-methoxy-3α,5-cyclo-24-methyl-5α-cholestan-22,23-diol diacetate

[26-(2)H3](22R,23R,24S)-24-methycholest-5-en-3β,22,23-triol 22,23-diacetate

p-toluenesulfonyl chloride