5b,11-Dihydroindolizino(1,2-b)quinolin-9(6H)-one

Base Information

Chemical Name:5b,11-Dihydroindolizino(1,2-b)quinolin-9(6H)-one
CAS No.:33568-61-5
Molecular Formula:C₁₅H₁₂N₂O
Molecular Weight:236.273
Hs Code.:
NSC Number:150560
UNII:ON6EEC5774

Synonyms:ON6EEC5774;33568-61-5;NSC-150560;5b,11-Dihydroindolizino(1,2-b)quinolin-9(6H)-one;NSC 150560;UNII-ON6EEC5774;NSC150560;INDOLIZINO(1,2-B)QUINOLIN-9(6H)-ONE, 5B,11-DIHYDRO-

Suppliers and Price of 5b,11-Dihydroindolizino(1,2-b)quinolin-9(6H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5b,11-Dihydroindolizino(1,2-b)quinolin-9(6H)-one

Chemical Property:

Vapor Pressure:9.32E-10mmHg at 25°C
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:236.094963011
Heavy Atom Count:18
Complexity:392

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C=CC(=O)N2C1C3=NC4=CC=CC=C4C=C3C2

Technology Process of 5b,11-Dihydroindolizino(1,2-b)quinolin-9(6H)-one

There total 7 articles about 5b,11-Dihydroindolizino(1,2-b)quinolin-9(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 776316-76-8
1-(3-allyl-1,3-dihydro-pyrrolo[3,4-b]quinolin-2-yl)-propenone

: 33568-61-5
5b,11-dihydro-6H-indolizino[1,2-b]quinolin-9-one

Guidance literature:: With titanium(IV) isopropylate; Grubbs catalyst first generation; In dichloromethane; Heating;
DOI:10.1016/j.tetlet.2004.07.101

Reference yield:

: 776316-76-8
1-(3-allyl-1,3-dihydro-pyrrolo[3,4-b]quinolin-2-yl)-propenone

: 30062-37-4
indolizino[1,2-b]quinolin-9(11H)-one

: 33568-61-5
5b,11-dihydro-6H-indolizino[1,2-b]quinolin-9-one

Guidance literature:: Grubbs catalyst first generation; In benzene; for 26h; Heating;
DOI:10.1016/j.tetlet.2004.07.101

Reference yield:

: 214191-31-8
3-Allyl-1,3-dihydro-pyrrolo[3,4-b]quinoline-2-carboxylic acid benzyl ester

: 33568-61-5
5b,11-dihydro-6H-indolizino[1,2-b]quinolin-9-one

Guidance literature:: Multi-step reaction with 3 steps

1: KOH / ethanol / 24 h / Heating

2: K₂CO₃ / CH₂Cl₂ / 3 h / 20 °C

3: Grubbs' 1st generation catalyst / benzene / 26 h / Heating

With potassium hydroxide; potassium carbonate; Grubbs catalyst first generation; In ethanol; dichloromethane; benzene;
DOI:10.1016/j.tetlet.2004.07.101