Technology Process of (+/-)-12-Benzoyloxyabieta-8,11,13-trien-6β,11-diol
There total 13 articles about (+/-)-12-Benzoyloxyabieta-8,11,13-trien-6β,11-diol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 11 steps
1: Li, naphthalene / tetrahydrofuran
2: CrO3, Py
3: polyphosphoric acid
4: CrO3, aq. H2SO4 / acetone
5: NaOAc
6: H2, aq. HClO4 / Pd-C / ethyl acetate
7: (i) Pb(OAc)4, AcOH, (ii) aq. HCl, EtOH
8: (i) MCPBA, CHCl3, (ii) aq. HCl, EtOH
9: BBr3 / CH2Cl2
10: LiAlH4 / diethyl ether
11: CHCl3
With
pyridine; chromium(VI) oxide; lithium aluminium tetrahydride; perchloric acid; PPA; naphthalene; sulfuric acid; hydrogen; sodium acetate; boron tribromide; lithium;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; dichloromethane; chloroform; ethyl acetate; acetone;
DOI:10.1246/bcsj.50.1575
- Guidance literature:
-
Multi-step reaction with 12 steps
1: SOCl2
2: Li, naphthalene / tetrahydrofuran
3: CrO3, Py
4: polyphosphoric acid
5: CrO3, aq. H2SO4 / acetone
6: NaOAc
7: H2, aq. HClO4 / Pd-C / ethyl acetate
8: (i) Pb(OAc)4, AcOH, (ii) aq. HCl, EtOH
9: (i) MCPBA, CHCl3, (ii) aq. HCl, EtOH
10: BBr3 / CH2Cl2
11: LiAlH4 / diethyl ether
12: CHCl3
With
pyridine; chromium(VI) oxide; lithium aluminium tetrahydride; thionyl chloride; perchloric acid; PPA; naphthalene; sulfuric acid; hydrogen; sodium acetate; boron tribromide; lithium;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; dichloromethane; chloroform; ethyl acetate; acetone;
DOI:10.1246/bcsj.50.1575
- Guidance literature:
-
Multi-step reaction with 10 steps
1: CrO3, Py
2: polyphosphoric acid
3: CrO3, aq. H2SO4 / acetone
4: NaOAc
5: H2, aq. HClO4 / Pd-C / ethyl acetate
6: (i) Pb(OAc)4, AcOH, (ii) aq. HCl, EtOH
7: (i) MCPBA, CHCl3, (ii) aq. HCl, EtOH
8: BBr3 / CH2Cl2
9: LiAlH4 / diethyl ether
10: CHCl3
With
pyridine; chromium(VI) oxide; lithium aluminium tetrahydride; perchloric acid; PPA; sulfuric acid; hydrogen; sodium acetate; boron tribromide;
palladium on activated charcoal;
In
diethyl ether; dichloromethane; chloroform; ethyl acetate; acetone;
DOI:10.1246/bcsj.50.1575