tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide

Base Information

• Chemical Name: tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide
• CAS No.: 110072-07-6
• Molecular Formula: C₂₆H₃₆N₄O₈S
• Molecular Weight: 564.66
• Mol file: 110072-07-6.mol

Synonyms:

Chemical Property of tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide

There total 5 articles about tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyloxycarbonyl-O-sulfotyrosine (116775-45-2) + H-Leu-NHNHPh*TFA (77162-15-3) → tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide (110072-07-6)

Guidance literature:

With calcium chloride; thermolysin; In ethanol; at 38 ℃; for 20h; Yield given;

Reference yield:

tert-butyloxycarbonyl-O-sulfotyrosine α-methyl ester (116775-41-8) + H-Leu-NHNHPh*TFA (77162-15-3) → tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide (110072-07-6)

Guidance literature:

With ethylenediaminetetraacetic acid; DL-cysteine hydrochloride; papain; In ethanol; at 30 ℃; for 30h; Yield given;

Reference yield:

tert-butyldicarbonate (34619-03-9) → tert-butyloxycarbonyl-O-sulfotyrosyl-leucine α-phenylhydrazide (110072-07-6)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / H₂O; dioxane / 4 h / Ambient temperature

2: thermolysin/CaCl₂ / ethanol; various solvent(s) / 20 h / 38 °C

With potassium hydroxide; calcium chloride; thermolysin; In 1,4-dioxane; ethanol; water;

upstream raw materials:

tert-butyloxycarbonyl-O-sulfotyrosine

H-Leu-NHNHPh*TFA

tert-butyloxycarbonyl-O-sulfotyrosine α-methyl ester

tert-butyldicarbonate