(2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid

Base Information

Chemical Name:(2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid
CAS No.:1375747-38-8
Molecular Formula:C₂HF₃O₂*C₂₃H₂₄Cl₂FN₃O₂
Molecular Weight:578.391
Hs Code.:

(2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid

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Chemical Property of (2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid

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Technology Process of (2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid

There total 2 articles about (2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1447829-74-4
C₃₇H₃₆Cl₂FN₃O₃

: 76-05-1
trifluoroacetic acid

: 1375747-38-8
(2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid

Guidance literature:: C₃₇H₃₆Cl₂FN₃O₃; With ammonium cerium (IV) nitrate; In water; acetonitrile; at 20 ℃; for 1h;

With sodium hydrogencarbonate; In water; acetonitrile; at 20 ℃; for 72h; pH=8;

trifluoroacetic acid; In water; acetonitrile;
DOI:10.1021/ja3125417

Reference yield:

: 1447829-74-4
C₃₇H₃₆Cl₂FN₃O₃

: 76-05-1
trifluoroacetic acid

: 1375747-38-8
(2′S,3R,4′S,5′R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid

: 1432582-25-6
(2'S,3S,4'S,5'R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide

: 1432582-51-8
(2'S,3S,4'S,5'R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide

Guidance literature:: C₃₇H₃₆Cl₂FN₃O₃; With ammonium cerium (IV) nitrate; In water; acetonitrile; at 20 ℃; for 1h;

trifluoroacetic acid; In water; acetonitrile;
DOI:10.1021/ja3125417