bisabol-3,7,11-trihydroxy

Base Information

• Chemical Name: bisabol-3,7,11-trihydroxy
• CAS No.: 121952-69-0
• Molecular Formula: C₁₅H₃₀O₃
• Molecular Weight: 258.401
• Mol file: 121952-69-0.mol

Synonyms:

Chemical Property of bisabol-3,7,11-trihydroxy

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bisabol-3,7,11-trihydroxy

There total 3 articles about bisabol-3,7,11-trihydroxy which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Hydroxy-5-(4-methyl-cyclohex-3-enyl)-hexanoic acid methyl ester (121952-67-8,121952-74-7) → bisabol-3,7,11-trihydroxy (121952-69-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.14 g / tetrahydrofuran; diethyl ether / -5 °C

2: 1.) Hg(OAc)2; 2.) NaBH₄ / 1.) H₂O, THF, 72 h

With sodium tetrahydroborate; mercury(II) diacetate; In tetrahydrofuran; diethyl ether;

DOI:10.1016/S0040-4020(01)86015-4

Reference yield:

limonene. (138-86-3,555-08-8,8022-90-0,9003-73-0,95327-98-3) → bisabol-3,7,11-trihydroxy (121952-69-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) Hg(OAc)2; 2.) NaBH₄ / 1.) THF, H₂O, 1 h; 2.) -80 degC

2: 1.14 g / tetrahydrofuran; diethyl ether / -5 °C

3: 1.) Hg(OAc)2; 2.) NaBH₄ / 1.) H₂O, THF, 72 h

With sodium tetrahydroborate; mercury(II) diacetate; In tetrahydrofuran; diethyl ether;

DOI:10.1016/S0040-4020(01)86015-4

Reference yield:

2-(4-methyl-3-cyclohexenyl)-6-methylheptan-2,6-diol (17844-29-0) → bisabol-11-hydroxy-3,7-oxide (121952-68-9) + bisabol-3,7,11-trihydroxy (121952-69-0)

Guidance literature:

With sodium tetrahydroborate; mercury(II) diacetate; Yield given. Multistep reaction. Yields of byproduct given; 1.) H₂O, THF, 72 h;

DOI:10.1016/S0040-4020(01)86015-4

upstream raw materials:

2-(4-methyl-3-cyclohexenyl)-6-methylheptan-2,6-diol

5-Hydroxy-5-(4-methyl-cyclohex-3-enyl)-hexanoic acid methyl ester

limonene.