Technology Process of 17β-tosyloxy-18-nor-5α,13β-androstane
There total 5 articles about 17β-tosyloxy-18-nor-5α,13β-androstane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 90 percent / NaBH4 / methanol / 2 h / ice temp. -> r.t.
2: pyridine
With
pyridine; sodium tetrahydroborate;
In
methanol;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82 percent / m-chloroperbenzoic acid
2: 10 percent / boron trifluoride
3: 90 percent / NaBH4 / methanol / 2 h / ice temp. -> r.t.
4: pyridine
With
pyridine; sodium tetrahydroborate; boron trifluoride; 3-chloro-benzenecarboperoxoic acid;
In
methanol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 56 percent / dicyclohexylcarbodiimide, CF3COOH / benzene; dimethylsulfoxide / 48 h / 25 °C
2: 82 percent / m-chloroperbenzoic acid
3: 10 percent / boron trifluoride
4: 90 percent / NaBH4 / methanol / 2 h / ice temp. -> r.t.
5: pyridine
With
pyridine; sodium tetrahydroborate; boron trifluoride; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
methanol; dimethyl sulfoxide; benzene;