Technology Process of 5-phenyl-11-tert-butyl-17-methyl-23-carbethoxy-25,26,27,28-tetrahydrocalix<4>arene
There total 8 articles about 5-phenyl-11-tert-butyl-17-methyl-23-carbethoxy-25,26,27,28-tetrahydrocalix<4>arene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
titanium tetrachloride;
In
1,4-dioxane;
for 90h;
Heating;
DOI:10.1021/jo00391a005
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 64 percent / toluene / 8 h / 90 °C
2: 71 percent / HBr, acetic acid / 2 h
3: 57 percent / toluene / 12 h / 100 °C
4: 73 percent / H2, KOH / Raney Ni / methanol / 760 Torr
5: 8.8 percent / TiCl4 / dioxane / 90 h / Heating
With
potassium hydroxide; hydrogen bromide; hydrogen; acetic acid;
titanium tetrachloride; nickel;
In
1,4-dioxane; methanol; toluene;
DOI:10.1021/jo00391a005
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 42 percent / HBr, acetic acid / 20 h
2: 64 percent / toluene / 8 h / 90 °C
3: 71 percent / HBr, acetic acid / 2 h
4: 57 percent / toluene / 12 h / 100 °C
5: 73 percent / H2, KOH / Raney Ni / methanol / 760 Torr
6: 8.8 percent / TiCl4 / dioxane / 90 h / Heating
With
potassium hydroxide; hydrogen bromide; hydrogen; acetic acid;
titanium tetrachloride; nickel;
In
1,4-dioxane; methanol; toluene;
DOI:10.1021/jo00391a005
