Methyl 2-[(tert-butoxycarbonyl)amino]-2-(trifluoromethyl)pent-4-enoate

Base Information

Chemical Name:Methyl 2-[(tert-butoxycarbonyl)amino]-2-(trifluoromethyl)pent-4-enoate
CAS No.:216235-33-5
Molecular Formula:C₁₂H₁₈F₃NO₄
Molecular Weight:297.274
Hs Code.:

Synonyms:METHYL 2-[(TERT-BUTOXYCARBONYL)AMINO]-2-(TRIFLUOROMETHYL)PENT-4-ENOATE;MFCD07779887;C12H18F3NO4;AKOS025212867;methyl 2-(tert-butoxycarbonylamino)-2-(trifluoromethyl)pent-4-enoate;METHYL 2-[(TERT-BUTOXYCARBONYL)AMINO]-2-(TRIFLUOROMETHYL) PENT-4-ENOATE;216235-33-5

Suppliers and Price of Methyl 2-[(tert-butoxycarbonyl)amino]-2-(trifluoromethyl)pent-4-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 2-[(tert-butoxycarbonyl)amino]-2-(trifluoromethyl)pent-4-enoate

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:297.11879254
Heavy Atom Count:20
Complexity:387

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC=C)(C(=O)OC)C(F)(F)F

Technology Process of Methyl 2-[(tert-butoxycarbonyl)amino]-2-(trifluoromethyl)pent-4-enoate

There total 2 articles about Methyl 2-[(tert-butoxycarbonyl)amino]-2-(trifluoromethyl)pent-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: methyl 2-[N-(tert-butoxycarbonyl)imino]-3,3,3-trifluoropropionate

: 1730-25-2
allylmagnesium bromide

: 216235-33-5
2d

Guidance literature:: In tetrahydrofuran; 1.) -100 deg C, 1 h, 2.) -100 deg C to r.t., 2 h;
DOI:10.1039/a804792h

Reference yield:

: 126535-89-5
methyl 2-[(tert-butoxycarbonyl)imino]-3,3,3-trifluoropropanoate

: 1730-25-2
allylmagnesium bromide

: 216235-33-5
2d

Guidance literature:: Inert atmosphere;
DOI:10.1002/chem.201101209

Reference yield: 55.0%

: 106-95-6
allyl bromide

: 216235-33-5
2d

: methyl 2-[(tert-butoxycarbonyl)(prop-2-enyl)amino]-2-(trifluoromethyl)pent-4-enoate

Guidance literature:: With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 8h;
DOI:10.1002/1099-0690(200110)2001:20<3891::AID-EJOC3891>3.0.CO;2-R