pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂

Base Information

Chemical Name:pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂
CAS No.:104061-30-5
Molecular Formula:C₃₆H₄₉N₇O₇S
Molecular Weight:723.894
Hs Code.:

pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH<sub>2</sub>

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂

Chemical Property:

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Technology Process of pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂

There total 4 articles about pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 40297-96-9
H-Gly-Leu-Met-NH₂ hydrochloride

: 104061-33-8
pGlu-gPhe-(RS)-mPhe-OH

: 104061-30-5
pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; for 12h; Ambient temperature;

Reference yield:

: 104061-32-7
pGlu-gPhe-(RS)-mPhe-OBzl

: 104061-30-5
pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen, acetic acid / 10percent Pd-C / methanol / 3620.04 Torr

2: 25 percent / N-methylmorpholine, 1-hydroxy benzotriazole, N-ethyl N'(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 12 h / Ambient temperature

With 4-methyl-morpholine; hydrogen; benzotriazol-1-ol; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;

Reference yield:

: 3235-59-4
Boc-Gly-Leu-Met-NH₂

: 104061-30-5
pGlu-gPhe-(RS)-mPhe-Gly-Leu-Met-NH₂

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / HCl, thioanisole / ethyl acetate / 0.5 h / Ambient temperature

2: 25 percent / N-methylmorpholine, 1-hydroxy benzotriazole, N-ethyl N'(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 12 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; methyl-phenyl-thioether; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In ethyl acetate; N,N-dimethyl-formamide;