Octahydro-pentalene-1-carboxylic acid phenylamide

Base Information

• Chemical Name: Octahydro-pentalene-1-carboxylic acid phenylamide
• CAS No.: 92651-70-2
• Molecular Formula: C₁₅H₁₉NO
• Molecular Weight: 229.322
• Mol file: 92651-70-2.mol

Synonyms:

Chemical Property of Octahydro-pentalene-1-carboxylic acid phenylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Octahydro-pentalene-1-carboxylic acid phenylamide

There total 2 articles about Octahydro-pentalene-1-carboxylic acid phenylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.9%

((C6H11)3P)Ni((C6H5)NC(O)C8H12) + ((C6H11)3P)Ni((C6H5)NC(O)C8H12) → Octahydro-pentalene-1-carboxylic acid phenylamide (92651-70-2) + Octahydro-pentalene-2-carboxylic acid phenylamide (108839-92-5)

Guidance literature:

With hydrogenchloride; In diethyl ether; to a suspn. of the azanickelacyclopentanone was added HCl/Et2O at -78°C in the absence of air and the mixt. warmed to room temp. overnight;; addn. of H2O, washing with Et2O, drying over MgSO4, removing of the solvent, chromy., m.p., IR, NMR, MS;

DOI:10.1016/0022-328X(91)86057-W

Reference yield:

bicyclo[3.3.0]oct-2-ene (5549-09-7) + phenyl isocyanate (103-71-9) → Octahydro-pentalene-1-carboxylic acid phenylamide (92651-70-2) + Octahydro-pentalene-2-carboxylic acid phenylamide (108839-92-5)

Guidance literature:

With hydrogenchloride; bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; Yield given. Multistep reaction. Yields of byproduct given; 1.) Et₂O, -10 deg C, 2 h, 2.) Et₂O, -78 deg C to RT;

DOI:10.1016/0022-328X(91)86057-W

upstream raw materials:

bicyclo[3.3.0]oct-2-ene

phenyl isocyanate