C₅₃H₇₆N₄O₃

Base Information

• Chemical Name: C₅₃H₇₆N₄O₃
• CAS No.: 1446275-82-6
• Molecular Formula: C₅₃H₇₆N₄O₃
• Molecular Weight: 817.211
• Mol file: 1446275-82-6.mol

Synonyms:

Chemical Property of C₅₃H₇₆N₄O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₃H₇₆N₄O₃

There total 3 articles about C₅₃H₇₆N₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → C53H76N4O3 (1446275-82-6)

Guidance literature:

Multi-step reaction with 5 steps

1: hydrogenchloride; sodium nitrite / water / 0.17 h / 0 - 5 °C

2: copper(l) iodide / tetrahydrofuran / Reflux; Inert atmosphere

3: dicyclohexyl-carbodiimide; dmap / dichloromethane / 12 h / Inert atmosphere

4: ammonium chloride; iron / ethanol / 1 h / 85 °C

5: hydrogenchloride / 1 h / Reflux

With hydrogenchloride; dmap; copper(l) iodide; iron; ammonium chloride; dicyclohexyl-carbodiimide; sodium nitrite; In tetrahydrofuran; ethanol; dichloromethane; water;

DOI:10.1039/c3nj00053b

Reference yield:

1-p-nitrophenyl-1H-[1,2,3]-triazole 4-carboxylic acid (4600-06-0) → C53H76N4O3 (1446275-82-6)

Guidance literature:

Multi-step reaction with 3 steps

1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 12 h / Inert atmosphere

2: ammonium chloride; iron / ethanol / 1 h / 85 °C

3: hydrogenchloride / 1 h / Reflux

With hydrogenchloride; dmap; iron; ammonium chloride; dicyclohexyl-carbodiimide; In ethanol; dichloromethane;

DOI:10.1039/c3nj00053b

Reference yield:

4-nitrophenyl azide (1516-60-5) → C53H76N4O3 (1446275-82-6)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(l) iodide / tetrahydrofuran / Reflux; Inert atmosphere

2: dicyclohexyl-carbodiimide; dmap / dichloromethane / 12 h / Inert atmosphere

3: ammonium chloride; iron / ethanol / 1 h / 85 °C

4: hydrogenchloride / 1 h / Reflux

With hydrogenchloride; dmap; copper(l) iodide; iron; ammonium chloride; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1039/c3nj00053b

upstream raw materials:

4-nitro-aniline

4-nitrophenyl azide

1-p-nitrophenyl-1H-[1,2,3]-triazole 4-carboxylic acid