Technology Process of 2-<(S)-Phenylsulfinyl>acrylsaeuremethylester
There total 5 articles about 2-<(S)-Phenylsulfinyl>acrylsaeuremethylester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 40 percent / 30percent aq. H2O2 / acetone / 1.) 0 deg C, 4 h, 2.) room temperature, 24 h
2: 92 percent / methanol; diethyl ether
3: 1.) HMDS, BuLi / 1.) THF, hexane, -78 deg C, 5 min, 2.) THF, a) -110 deg C, b) -110 deg C -> room temperature
4: NaBrO2*3H2O / dioxane; H2O / 2 h / Ambient temperature
With
n-butyllithium; sodium bromite; dihydrogen peroxide; 1,1,1,3,3,3-hexamethyl-disilazane;
In
1,4-dioxane; methanol; diethyl ether; water; acetone;
DOI:10.1055/s-1992-26328
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 93 percent / 4 N HCl / acetone / 6 h / Heating
2: 40 percent / 30percent aq. H2O2 / acetone / 1.) 0 deg C, 4 h, 2.) room temperature, 24 h
3: 92 percent / methanol; diethyl ether
4: 1.) HMDS, BuLi / 1.) THF, hexane, -78 deg C, 5 min, 2.) THF, a) -110 deg C, b) -110 deg C -> room temperature
5: NaBrO2*3H2O / dioxane; H2O / 2 h / Ambient temperature
With
hydrogenchloride; n-butyllithium; sodium bromite; dihydrogen peroxide; 1,1,1,3,3,3-hexamethyl-disilazane;
In
1,4-dioxane; methanol; diethyl ether; water; acetone;
DOI:10.1055/s-1992-26328
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 92 percent / methanol; diethyl ether
2: 1.) HMDS, BuLi / 1.) THF, hexane, -78 deg C, 5 min, 2.) THF, a) -110 deg C, b) -110 deg C -> room temperature
3: NaBrO2*3H2O / dioxane; H2O / 2 h / Ambient temperature
With
n-butyllithium; sodium bromite; 1,1,1,3,3,3-hexamethyl-disilazane;
In
1,4-dioxane; methanol; diethyl ether; water;
DOI:10.1055/s-1992-26328
