6-chloro-5-iodo-1H-indole

Base Information

Chemical Name:6-chloro-5-iodo-1H-indole
CAS No.:122509-74-4
Molecular Formula:C₈H₅ClIN
Molecular Weight:277.492
Hs Code.:
DSSTox Substance ID:DTXSID301312093
Mol file:122509-74-4.mol

Synonyms:6-chloro-5-iodo-1H-indole;122509-74-4;6-Chloro-5-iodoindole;SCHEMBL8527499;AMY9877;DTXSID301312093;ZB0404;SB15183;CS-0360997

Suppliers and Price of 6-chloro-5-iodo-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-5-iodoindole
10mg
$ 130.00

Crysdot
6-Chloro-5-iodo-1H-indole 95+%
1g
$ 451.00

Chemenu
6-Chloro-5-iodo-1H-indole 95%
1g
$ 425.00

Total 12 raw suppliers

Chemical Property of 6-chloro-5-iodo-1H-indole

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:0
Exact Mass:276.91552
Heavy Atom Count:11
Complexity:153

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-5-iodoindole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC2=CC(=C(C=C21)I)Cl

Technology Process of 6-chloro-5-iodo-1H-indole

There total 3 articles about 6-chloro-5-iodo-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 135050-44-1
3-chloro-4-iodoaniline

: 122509-74-4
6-Chloro-5-iodo-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / CH₂Cl₂ / 2 h

2: NaH / dimethylformamide / 0 °C

3: 1.) TiCl₄, 2.) aq. NaOH / 1.) toluene, 2 h, 2.) EtOH, reflux, 0.5 h

With pyridine; sodium hydroxide; titanium tetrachloride; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm970741j

Reference yield:

: 143937-73-9
N-(3-chloro-4-iodophenyl)methanesulfonamide

: 122509-74-4
6-Chloro-5-iodo-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 0 °C

2: 1.) TiCl₄, 2.) aq. NaOH / 1.) toluene, 2 h, 2.) EtOH, reflux, 0.5 h

With sodium hydroxide; titanium tetrachloride; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1021/jm970741j

Reference yield:

: N-(3-Chloro-4-iodo-phenyl)-N-(2,2-diethoxy-ethyl)-methanesulfonamide

: 122509-74-4
6-Chloro-5-iodo-1H-indole

: 4-Chloro-5-iodo-1H-indole

Guidance literature:: With sodium hydroxide; titanium tetrachloride; Multistep reaction; 1.) toluene, 2 h, 2.) EtOH, reflux, 0.5 h;
DOI:10.1021/jm970741j