5'-O-(dimethoxytrityl)-2'-O-uridine

Base Information

• Chemical Name: 5'-O-(dimethoxytrityl)-2'-O-uridine
• CAS No.: 165381-02-2
• Molecular Formula: C₅₆H₅₇N₃O₉
• Molecular Weight: 916.083
• Mol file: 165381-02-2.mol

Synonyms:

Chemical Property of 5'-O-(dimethoxytrityl)-2'-O-uridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-(dimethoxytrityl)-2'-O-uridine

There total 3 articles about 5'-O-(dimethoxytrityl)-2'-O-uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5'-O-(dimethoxytrityl)-2'-O-uridine (156881-45-7) → 5'-O-(dimethoxytrityl)-2'-O-uridine (165381-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine / methanol / Heating

With hydrazine; In methanol;

DOI:10.1021/j100048a024

Reference yield:

2,3’-O-dibutylstannyleneuridine (42822-78-6) → 5'-O-(dimethoxytrityl)-2'-O-uridine (165381-02-2)

Guidance literature:

Multi-step reaction with 3 steps

2: hydrazine / methanol / Heating

With hydrazine; In methanol;

DOI:10.1021/j100048a024

Reference yield:

5'-O-(dimethoxytrityl)-2'-O-(hexylamino)uridine (165381-00-0) + pentafluorophenyl ester of 4-(1-pyrenyl)butanoic acid (143039-32-1) → 5'-O-(dimethoxytrityl)-2'-O-uridine (165381-02-2)

Guidance literature:

DOI:10.1021/j100048a024

upstream raw materials:

5'-O-(dimethoxytrityl)-2'-O-(hexylamino)uridine

pentafluorophenyl ester of 4-(1-pyrenyl)butanoic acid

5'-O-(dimethoxytrityl)-2'-O-uridine

2,3’-O-dibutylstannyleneuridine