2-Amino-N-(4-chlorophenyl)-3-methylbenzamide

Base Information

Chemical Name:2-Amino-N-(4-chlorophenyl)-3-methylbenzamide
CAS No.:953884-54-3
Molecular Formula:C₁₄H₁₃ClN₂O
Molecular Weight:260.723
Hs Code.:
DSSTox Substance ID:DTXSID901257839

Synonyms:2-AMINO-N-(4-CHLOROPHENYL)-3-METHYLBENZAMIDE;SCHEMBL6592137;FHRZPSQNBQXLLC-UHFFFAOYSA-N;DTXSID901257839;AKOS000138161;953884-54-3;N-(4-chlorophenyl)-2-amino-3-methylbenzamide

Suppliers and Price of 2-Amino-N-(4-chlorophenyl)-3-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Amino-N-(4-chlorophenyl)-3-methylbenzamide

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:260.0716407
Heavy Atom Count:18
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)C(=O)NC2=CC=C(C=C2)Cl)N

Technology Process of 2-Amino-N-(4-chlorophenyl)-3-methylbenzamide

There total 4 articles about 2-Amino-N-(4-chlorophenyl)-3-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 600126-71-4
N-(4-chloro-phenyl)-3-methyl-2-nitro-benzamide

: 953884-54-3
N-(4-chlorophenyl)-2-amino-3-methylbenzamide

Guidance literature:: With tin(ll) chloride; In ethyl acetate; Heating;
DOI:10.1016/S0960-894X(02)00938-1

Reference yield:

: 5437-38-7
3-methyl-2-nitrobenzoic acid

: 953884-54-3
N-(4-chlorophenyl)-2-amino-3-methylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂; DMF / CH₂Cl₂ / 20 °C

2: NEt₃ / CH₂Cl₂ / 20 °C

3: SnCl₂*2H₂O / ethyl acetate / Heating

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; tin(ll) chloride; In dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(02)00938-1

Reference yield:

: 50424-93-6
3-methyl-2-nitrobenzoyl chloride

: 953884-54-3
N-(4-chlorophenyl)-2-amino-3-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: NEt₃ / CH₂Cl₂ / 20 °C

2: SnCl₂*2H₂O / ethyl acetate / Heating

With triethylamine; tin(ll) chloride; In dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(02)00938-1