3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide

Base Information

Chemical Name:3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide
CAS No.:165066-43-3
Molecular Formula:C₁₄H₁₇N₃OS
Molecular Weight:275.374
Hs Code.:
DSSTox Substance ID:DTXSID901327747
ChEMBL ID:CHEMBL1089006
Mol file:165066-43-3.mol

Synonyms:3-amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide;165066-43-3;CHEMBL1089006;6-amino-4-thia-2-azatricyclo[7.6.0.0^{3,7}]pentadeca-1,3(7),5,8-tetraene-5-carboxamide;6-amino-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1,3(7),5,8-tetraene-5-carboxamide;Oprea1_293242;MLS000779880;DTXSID901327747;HMS2806B12;BDBM50314407;STK781920;AKOS001748977;SS-0023;SMR000420066;CS-0324228;3-Amino-5,6,7,8,9,10-hexahydro-1-thia-11-aza-cycloocta[f]indene-2-carboxylic acid amide

Suppliers and Price of 3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-AMINO-5,6,7,8,9,10-HEXAHYDROCYCLOOCTA[B]THIENO[3,2-E]PYRIDINE-2-CARBOXAMIDE 95.00%
5MG
$ 633.99

American Custom Chemicals Corporation
3-AMINO-5,6,7,8,9,10-HEXAHYDROCYCLOOCTA[B]THIENO[3,2-E]PYRIDINE-2-CARBOXAMIDE 95.00%
10MG
$ 631.85

American Custom Chemicals Corporation
3-AMINO-5,6,7,8,9,10-HEXAHYDROCYCLOOCTA[B]THIENO[3,2-E]PYRIDINE-2-CARBOXAMIDE 95.00%
1MG
$ 597.89

Total 3 raw suppliers

Chemical Property of 3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:275.10923335
Heavy Atom Count:19
Complexity:352

Purity/Quality:

99% ^*data from raw suppliers

3-AMINO-5,6,7,8,9,10-HEXAHYDROCYCLOOCTA[B]THIENO[3,2-E]PYRIDINE-2-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:

Useful:

Canonical SMILES:C1CCCC2=NC3=C(C=C2CC1)C(=C(S3)C(=O)N)N

Technology Process of 3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide

There total 3 articles about 3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 154384-02-8
2-thioxo-1,2,5,6,7,8,9,10-octahydrocycloocta[b]pyridine-3-carbonitrile

: 165066-43-3
3-amino-2-carbamoyl-5,6-hexamethylenethieno<2,3-b>pyridine

Guidance literature:: With potassium hydroxide; In N,N-dimethyl-formamide; for 0.5h;
DOI:10.1007/BF01169725

Reference yield:

: 502-49-8
cycloactanone

: 165066-43-3
3-amino-2-carbamoyl-5,6-hexamethylenethieno<2,3-b>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / Na, EtOH / diethyl ether

2: 61 percent / acetic acid; ethanol / 3 h / Heating

3: 99 percent / 10percent aq. KOH / dimethylformamide / 0.5 h

With potassium hydroxide; ethanol; sodium; In diethyl ether; ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1007/BF01169725

Reference yield:

: 2-hydroxymethylenecyclooctan-1-one sodium salt

: 165066-43-3
3-amino-2-carbamoyl-5,6-hexamethylenethieno<2,3-b>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / acetic acid; ethanol / 3 h / Heating

2: 99 percent / 10percent aq. KOH / dimethylformamide / 0.5 h

With potassium hydroxide; In ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1007/BF01169725